Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Vibrio is a genus of ubiquitous bacteria found in a wide variety of aquatic and marine
habitats; of the> 100 described Vibrio spp.,~ 12 cause infections in humans. Vibrio cholerae …

Background: With advances in sequencing technology and decreasing costs, the number of
phage genomes that have been sequenced has increased markedly in the past decade …

Horizontal gene transfer can trigger rapid shifts in bacterial evolution. Driven by a variety of
mobile genetic elements—in particular bacteriophages and plasmids—the ability to share …

Antibiotic-resistant pathogens are increasingly more prevalent and problematic. Traditional
antibiotics are no longer a viable option for dealing with these multidrug-resistant microbes …

Bacteriophage (phage) therapy, ie, the use of viruses that infect bacteria as antimicrobial
agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics …

Viruses that infect microbial hosts have traditionally been studied in laboratory settings with
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …

Background & Aims Patients with colorectal cancer (CRC) have a different gut microbiome
signature than individuals without CRC. Little is known about the viral component of CRC …

Vibrio cholerae uses a quorum-sensing (QS) system composed of the autoinducer 3, 5-
dimethylpyrazin-2-ol (DPO) and receptor VqmA (VqmA Vc), which together repress genes …

The world is on the cusp of a post-antibiotic era, but researchers and medical doctors have
found a way forward—by looking back at how infections were treated before the advent of …