Vitamin D: metabolism, molecular mechanism of action, and pleiotropic effects
1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …
Vitamin D and human health: lessons from vitamin D receptor null mice
R Bouillon, G Carmeliet, L Verlinden… - Endocrine …, 2008 - academic.oup.com
The vitamin D endocrine system is essential for calcium and bone homeostasis. The precise
mode of action and the full spectrum of activities of the vitamin D hormone, 1, 25 …
mode of action and the full spectrum of activities of the vitamin D hormone, 1, 25 …
[HTML][HTML] Calcium intake, calcium homeostasis and health
Calcium, as the most abundant mineral in human body, is involved in many physiological
and pathological processes. Here, we reviewed the key mechanisms of calcium …
and pathological processes. Here, we reviewed the key mechanisms of calcium …
Vitamin D, hypercalciuria and kidney stones
E Letavernier, M Daudon - Nutrients, 2018 - mdpi.com
The estimated lifetime risk of nephrolithiasis is growing nowadays, and the formation of
kidney stones is frequently promoted by hypercalciuria. Vitamin D, and especially its active …
kidney stones is frequently promoted by hypercalciuria. Vitamin D, and especially its active …
Calcium and phosphate homeostasis: concerted interplay of new regulators
Calcium (Ca2+) and phosphate (Pi) are essential to many vital physiological processes.
Consequently the maintenance of Ca2+ and Pi homeostasis is essential to a healthy …
Consequently the maintenance of Ca2+ and Pi homeostasis is essential to a healthy …
The distal convoluted tubule
The distal tubule of the mammalian kidney can be defined as the nephron segment between
the macula densa region and the cortical collecting tubule. It comprises several …
the macula densa region and the cortical collecting tubule. It comprises several …
Regulation of transport in the connecting tubule and cortical collecting duct
The central goal of this overview article is to summarize recent findings in renal epithelial
transport, focusing chiefly on the connecting tubule (CNT) and the cortical collecting duct …
transport, focusing chiefly on the connecting tubule (CNT) and the cortical collecting duct …
Active Ca2+ reabsorption in the connecting tubule
The kidney plays a crucial role in the maintenance of the body calcium (Ca 2+) balance. Ca
2+ is an essential ion in all organisms and participates in a large variety of structural and …
2+ is an essential ion in all organisms and participates in a large variety of structural and …
Calciotropic and magnesiotropic TRP channels
Significant progress has been made into our understanding of the molecular mechanisms
responsible for Ca2+ and Mg2+ homeostasis. Members of the transient receptor potential …
responsible for Ca2+ and Mg2+ homeostasis. Members of the transient receptor potential …
Oxoglaucine mediates Ca2+ influx and activates autophagy to alleviate osteoarthritis through the TRPV5/calmodulin/CAMK‐II pathway
Background and Purpose Stimulation of calcium influx and suppression of autophagy play
important roles in the pathogenesis of osteoarthritis (OA). In this study, we used a novel …
important roles in the pathogenesis of osteoarthritis (OA). In this study, we used a novel …