Dydrogesterone as an oral alternative to vaginal progesterone for IVF luteal phase support: A systematic review and individual participant data meta-analysis

G Griesinger, C Blockeel, E Kahler, C Pexman-Fieth… - PLoS …, 2020 - journals.plos.org
The aim of this systematic review and meta-analysis was to conduct a comprehensive
assessment of the evidence on the efficacy and safety of oral dydrogesterone versus …

Dydrogesterone: pharmacological profile and mechanism of action as luteal phase support in assisted reproduction

G Griesinger, H Tournaye, N Macklon… - Reproductive …, 2019 - Elsevier
The pharmacological and physiological profiles of progestogens used for luteal phase
support during assisted reproductive technology are likely to be important in guiding clinical …

Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)

W Gao, JT Dalton - Drug discovery today, 2007 - Elsevier
Selective androgen receptor modulators (SARMs) are a novel class of androgen receptor
(AR) ligands that might change the future of androgen therapy dramatically. With improved …

The effect of variations in phospholipid and sterol structure on the nature of lipid–sterol interactions in lipid bilayer model membranes

DA Mannock, RNAH Lewis, TPW McMullen… - Chemistry and physics …, 2010 - Elsevier
This review deals with the effect of variations in phospholipid and sterol structure on the
nature and magnitude of lipid-sterol interactions in lipid bilayer model membranes. The first …

Progestational effects of dydrogesterone in vitro, in vivo and on the human endometrium

AE Schindler - Maturitas, 2009 - Elsevier
Dydrogesterone has a molecular structure closely related to that of natural progesterone, but
it has enhanced oral availability compared with progesterone. The hormonal profile and the …

Selectivity and potency of the retroprogesterone dydrogesterone in vitro

TL Rižner, P Brožič, C Doucette, T Turek-Etienne… - Steroids, 2011 - Elsevier
Dydrogesterone is widely used for menstrual disorders, endometriosis, threatened and
habitual abortion and postmenopausal hormone replacement therapy. Although progestins …

[HTML][HTML] Prolonged cyclical and continuous regimens of dydrogesterone are effective for reducing chronic pelvic pain in women with endometriosis: results of the …

GT Sukhikh, LV Adamyan, SO Dubrovina, II Baranov… - Fertility and …, 2021 - Elsevier
Objective To compare the effectiveness of two different treatment regimens of
dydrogesterone in the management of endometriosis-related chronic pelvic pain. Design …

Birth defects reporting and the use of dydrogesterone: a disproportionality analysis from the World Health Organization pharmacovigilance database (VigiBase)

A Henry, P Santulli, M Bourdon… - Human …, 2025 - academic.oup.com
STUDY QUESTION Is there an association between dydrogesterone exposure during early
pregnancy and the reporting of birth defects? SUMMARY ANSWER This observational …

The other side of progestins: effects in the brain

S Giatti, RC Melcangi… - Journal of Molecular …, 2016 - jme.bioscientifica.com
Progestins are a broad class of progestational agents widely differing in their chemical
structures and pharmacological properties. Despite emerging data suggest that progestins …

Ultra-low-dose estradiol and dydrogesterone for treatment of vasomotor symptoms in Europe and China

Q Yu, JC Stevenson, T Tatarchuk, RE Nappi… - …, 2024 - Taylor & Francis
Objective Among postmenopausal women, oral, ultra-low-dose continuous combined
estradiol (E0. 5 mg) plus dydrogesterone (D2. 5 mg) reduces vasomotor symptoms (VMS) …