Immune-related toxicities of checkpoint inhibitors: mechanisms and mitigation strategies

RJ Sullivan, JS Weber - Nature reviews Drug discovery, 2022 - nature.com
The immune-related adverse events associated with treatment with immune checkpoint
inhibitors result in significant morbidity for patients as well as considerable cost to the health …

Autoantibodies in neurological disease

H Prüss - Nature reviews immunology, 2021 - nature.com
The realization that autoantibodies can contribute to dysfunction of the brain has brought
about a paradigm shift in neurological diseases over the past decade, offering up important …

Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …

L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …

Neurologic adverse events of immune checkpoint inhibitors: a systematic review

A Marini, A Bernardini, GL Gigli, M Valente… - Neurology, 2021 - AAN Enterprises
Objective To define the clinical characteristics, management, and outcome of neurologic
immune-related adverse events (n-irAEs) of immune checkpoint inhibitors (ICIs). Methods …

Encephalitis induced by immune checkpoint inhibitors: a systematic review

R Velasco, M Villagrán, M Jové, M Simó… - JAMA …, 2021 - jamanetwork.com
Importance Encephalitis is a severe immune-related adverse event secondary to treatment
with immune checkpoint inhibitors (ICIs). The spectrum of ICI-induced encephalitis (ICI-iE) …

Epidemiology of paraneoplastic neurologic syndromes and autoimmune encephalitides in France

J Hébert, B Riche, A Vogrig… - Neurology …, 2020 - AAN Enterprises
Objective To determine the observed and expected incidence rates of paraneoplastic
neurologic syndromes (PNSs) and autoimmune encephalitides (AEs) diagnosed in France …

Paraneoplastic neurological syndromes: a practical approach to diagnosis and management

S Binks, C Uy, J Honnorat, SR Irani - Practical Neurology, 2022 - pn.bmj.com
Paraneoplastic neurological syndromes (PNS) are the immune-mediated effects of a remote
cancer and are characterised by an autoantibody response against antigens expressed by …

Antibody-mediated autoimmune diseases of the CNS: challenges and approaches to diagnosis and management

E Sechi, EP Flanagan - Frontiers in neurology, 2021 - frontiersin.org
Antibody-mediated disorders of the central nervous system (CNS) are increasingly
recognized as neurologic disorders that can be severe and even life-threatening but with the …

Neurological outcomes in immune checkpoint inhibitor-related neurotoxicity

A Farina, C Birzu, MH Elsensohn, A Picca… - Brain …, 2023 - academic.oup.com
While the spectrum of neurological immune checkpoint inhibitor-related adverse events is
expanding, patients' outcomes are not well documented. This study aimed to assess …

[HTML][HTML] Neurological complications of cancer immunotherapy

P Roth, S Winklhofer, AMS Müller, R Dummer… - Cancer Treatment …, 2021 - Elsevier
Immunotherapy has emerged as a powerful therapeutic approach in many areas of clinical
oncology and hematology. The approval of ipilimumab, a monoclonal antibody targeting the …