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Polymeric delivery of therapeutic nucleic acids
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Recent progress in the science of complex coacervation
Complex coacervation is an associative, liquid–liquid phase separation that can occur in
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …
solutions of oppositely-charged macromolecular species, such as proteins, polymers, and …
Driving force and pathway in polyelectrolyte complex coacervation
There is notable discrepancy between experiments and coarse-grained model studies
regarding the thermodynamic driving force in polyelectrolyte complex coacervation …
regarding the thermodynamic driving force in polyelectrolyte complex coacervation …
Modeling and simulations of polymers: a roadmap
Molecular modeling and simulations are invaluable tools for the polymer science and
engineering community. These computational approaches enable predictions and provide …
engineering community. These computational approaches enable predictions and provide …
Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …
50th Anniversary Perspective: A Perspective on Polyelectrolyte Solutions
M Muthukumar - Macromolecules, 2017 - ACS Publications
From the beginning of life with the information-containing polymers until the present era of a
plethora of water-based materials in health care industry and biotechnology, polyelectrolytes …
plethora of water-based materials in health care industry and biotechnology, polyelectrolytes …
Driving forces for oppositely charged polyion association in aqueous solutions: enthalpic, entropic, but not electrostatic
Driving forces for association between oppositely charged biological or synthetic polymers
in aqueous solution have long been identified as electrostatic in origin. This attraction is …
in aqueous solution have long been identified as electrostatic in origin. This attraction is …
Development of the modern theory of polymeric complex coacervation
CE Sing - Advances in colloid and interface science, 2017 - Elsevier
Oppositely charged polymers can undergo the process of complex coacervation, which
refers to a liquid–liquid phase separation driven by electrostatic attraction. These materials …
refers to a liquid–liquid phase separation driven by electrostatic attraction. These materials …
Recent advances in amino acid N-carboxyanhydrides and synthetic polypeptides: chemistry, self-assembly and biological applications
Polypeptides are fascinating materials with unique properties for various biological
materials. We highlight here recent advances in amino acid N-carboxyanhydrides (NCAs) …
materials. We highlight here recent advances in amino acid N-carboxyanhydrides (NCAs) …
Beyond lipids: exploring advances in polymeric gene delivery in the lipid nanoparticles era
The recent success of gene therapy during the COVID‐19 pandemic has underscored the
importance of effective and safe delivery systems. Complementing lipid‐based delivery …
importance of effective and safe delivery systems. Complementing lipid‐based delivery …