[HTML][HTML] Carnitine transport and fatty acid oxidation

N Longo, M Frigeni, M Pasquali - … et biophysica acta (BBA)-molecular cell …, 2016 - Elsevier
Carnitine is essential for the transfer of long-chain fatty acids across the inner mitochondrial
membrane for subsequent β-oxidation. It can be synthesized by the body or assumed with …

Emerging biomarkers in autism spectrum disorder: a systematic review

RE Frye, S Vassall, G Kaur, C Lewis… - Annals of …, 2019 - pmc.ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) affects approximately 2% of children in the United States
(US) yet its etiology is unclear and effective treatments are lacking. Therapeutic interventions …

Clinical and molecular characteristics of mitochondrial dysfunction in autism spectrum disorder

S Rose, DM Niyazov, DA Rossignol… - Molecular diagnosis & …, 2018 - Springer
Autism spectrum disorder (ASD) affects~ 2% of children in the United States. The etiology of
ASD likely involves environmental factors triggering physiological abnormalities in …

Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis

DA Rossignol, RE Frye - Molecular psychiatry, 2012 - nature.com
A comprehensive literature search was performed to collate evidence of mitochondrial
dysfunction in autism spectrum disorders (ASDs) with two primary objectives. First, features …

Carnitine and acylcarnitines: pharmacokinetic, pharmacological and clinical aspects

SE Reuter, AM Evans - Clinical pharmacokinetics, 2012 - Springer
L-Carnitine (levocarnitine) is a naturally occurring compound found in all mammalian
species. The most important biological function of L-carnitine is in the transport of fatty acids …

The role of the microbial metabolites including tryptophan catabolites and short chain fatty acids in the pathophysiology of immune-inflammatory and neuroimmune …

G Morris, M Berk, A Carvalho, JR Caso, Y Sanz… - Molecular …, 2017 - Springer
There is a growing awareness that gut commensal metabolites play a major role in host
physiology and indeed the pathophysiology of several illnesses. The composition of the …

[HTML][HTML] Comprehensive nutritional and dietary intervention for autism spectrum disorder—a randomized, controlled 12-month trial

JB Adams, T Audhya, E Geis, E Gehn, V Fimbres… - Nutrients, 2018 - mdpi.com
This study involved a randomized, controlled, single-blind 12-month treatment study of a
comprehensive nutritional and dietary intervention. Participants were 67 children and adults …

Identification and evaluation of children with autism spectrum disorders

CP Johnson, SM Myers - Pediatrics, 2007 - publications.aap.org
Autism spectrum disorders are not rare; many primary care pediatricians care for several
children with autism spectrum disorders. Pediatricians play an important role in early …

Social skills deficits in autism spectrum disorder: potential biological origins and progress in develo** therapeutic agents

RE Frye - CNS drugs, 2018 - Springer
Autism spectrum disorder is defined by two core symptoms: a deficit in social communication
and the presence of repetitive behaviors and/or restricted interests. Currently, there is no US …

Elevated fecal short chain fatty acid and ammonia concentrations in children with autism spectrum disorder

L Wang, CT Christophersen, MJ Sorich… - Digestive diseases and …, 2012 - Springer
Abstract Background and Aim Autism spectrum disorder (ASD) is a complex
neurodevelopmental disorder where a high frequency of gastrointestinal disturbance (eg …