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Runs of homozygosity: windows into population history and trait architecture
Long runs of homozygosity (ROH) arise when identical haplotypes are inherited from each
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …
Tracing the peopling of the world through genomics
Advances in the sequencing and the analysis of the genomes of both modern and ancient
peoples have facilitated a number of breakthroughs in our understanding of human …
peoples have facilitated a number of breakthroughs in our understanding of human …
The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …
While the raw data for the vast majority are fully publicly available testifying to the …
Palaeogenomics of upper palaeolithic to neolithic European hunter-gatherers
Modern humans have populated Europe for more than 45,000 years,. Our knowledge of the
genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to …
genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to …
Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations
Multiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …
prevalent in Northern Europe. Although it is known that inherited risk for MS is located within …
Grey wolf genomic history reveals a dual ancestry of dogs
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and
they remained widespread throughout the last Ice Age when many other large mammal …
they remained widespread throughout the last Ice Age when many other large mammal …
The genetic history of the Southern Arc: A bridge between West Asia and Europe
By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …
Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry
Modern humans appeared in Europe by at least 45,000 years ago,,,–, but the extent of their
interactions with Neanderthals, who disappeared by about 40,000 years ago, and their …
interactions with Neanderthals, who disappeared by about 40,000 years ago, and their …
Language trees with sampled ancestors support a hybrid model for the origin of Indo-European languages
The origins of the Indo-European language family are hotly disputed. Bayesian phylogenetic
analyses of core vocabulary have produced conflicting results, with some supporting a …
analyses of core vocabulary have produced conflicting results, with some supporting a …
The genomic history of the Iberian Peninsula over the past 8000 years
We assembled genome-wide data from 271 ancient Iberians, of whom 176 are from the
largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect …
largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect …