Rhabdomyolysis

BMI Cabral, SN Edding, JP Portocarrero, EV Lerma - Disease-a-Month, 2020 - Elsevier
Rhabdomyolysis is caused by the breakdown and necrosis of muscle tissue and the release
of intracellular content into the blood stream. There are multiple and diverse causes of …

Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice

LO Chavez, M Leon, S Einav, J Varon - Critical care, 2016 - Springer
Background Rhabdomyolysis is a clinical syndrome that comprises destruction of skeletal
muscle with outflow of intracellular muscle content into the bloodstream. There is a great …

Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non …

SW Pipe, M Shima, M Lehle, A Shapiro… - The Lancet …, 2019 - thelancet.com
Background Emicizumab, a subcutaneously administered, humanised, bispecific,
monoclonal antibody, is approved to treat people with haemophilia A of all ages with and …

ACSL4 contributes to ferroptosis‐mediated rhabdomyolysis in exertional heat stroke

S He, R Li, Y Peng, Z Wang, J Huang… - Journal of cachexia …, 2022 - Wiley Online Library
Background Rhabdomyolysis (RM) is a common complication of exertional heat stroke
(EHS) and constitutes a direct cause of death. However, the mechanism underlying RM …

Rhabdomyolysis and acute kidney injury

X Bosch, E Poch, JM Grau - New England Journal of Medicine, 2009 - Mass Medical Soc
The causes of acute rhabdomyolysis include trauma, drugs, toxins, and certain infections.
Acute kidney injury is a dangerous complication of severe rhabdomyolysis. This review …

A synopsis of current theories on drug-induced nephrotoxicity

L Dobrek - Life, 2023 - mdpi.com
The overriding goal of the treatment of patients is its effectiveness and safety. However, all
medications currently being used also exert some adverse pharmaceutical reactions, which …

Rhabdomyolysis

JL Zimmerman, MC Shen - Chest, 2013 - Elsevier
Rhabdomyolysis is a well-known clinical syndrome of muscle injury associated with
myoglobinuria, electrolyte abnormalities, and often acute kidney injury (AKI). The …

Abnormal liver function tests associated with severe rhabdomyolysis

AKH Lim - World journal of gastroenterology, 2020 - pmc.ncbi.nlm.nih.gov
Rhabdomyolysis is a syndrome of skeletal muscle injury with release of cellular constituents
such as potassium, phosphate, urate and intracellular proteins such as myoglobin into the …

Rhabdomyolysis: revisited

A Gupta, P Thorson, KR Penmatsa… - The Ulster medical …, 2021 - pmc.ncbi.nlm.nih.gov
Rhabdomyolysis (RML) is a pathological entity characterized by symptoms of myalgia,
weakness and dark urine (which is often not present) resulting in respiratory failure and …

Rhabdomyolysis

GL Stone, FE Nácul, JM O'Donnell - Surgical Intensive Care Medicine, 2016 - Springer
Rhabdomyolysis is a potentially life-threatening syndrome resulting from the destruction of
striated muscle with leakage of muscle enzymes, myoglobin, potassium, phosphate, uric …