RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Recent mechanistic studies have attempted to deepen our understanding of the process by
which liposome-mediated delivery of genetic material occurs. Understanding the …

The present work highlights recent achievements in development of nanostructured
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …

Gene therapy is a promising technique for the treatment of various diseases. The
development of minimally toxic and highly efficient non-viral gene delivery vectors is the …

Recently developed macromolecular drugs display strong potential to cure diseases
involving genetic components, eg Rheumatoid arthritis, diabetes, Alzheimer's disease …

Interactions of anions with hydrophobic surfaces of proteins and water-soluble polymers
depend on the ability of the ions to shed their hydration shells. At positively charged …

Subunit vaccines rely on adjuvants carrying one or a few molecular antigens from the
pathogen in order to guarantee an improved immune response. However, to be effective, the …

There is an increasing need for novel drugs and new strategies for the therapy of invasive
candidiasis. This study aimed to develop and characterize liposome-based nanoparticles of …

This study describes a novel liposomal formulation for siRNA delivery, based on the mixture
of the neutral lipid monoolein (MO) and cationic lipids of the dioctadecyldimethylammonium …

Cationic lipid membranes have recently attracted huge attention both from a fundamental
point of view and due to their practical applications in drug delivery and gene therapy. The …