Cancer epigenetics: From laboratory studies and clinical trials to precision medicine

X Yu, H Zhao, R Wang, Y Chen, X Ouyang, W Li… - Cell Death …, 2024 - nature.com
Epigenetic dysregulation is a common feature of a myriad of human diseases, particularly
cancer. Defining the epigenetic defects associated with malignant tumors has become a …

[HTML][HTML] Next generation and other sequencing technologies in diagnostic microbiology and infectious diseases

EE Hilt, P Ferrieri - Genes, 2022 - mdpi.com
Next-generation sequencing (NGS) technologies have become increasingly available for
use in the clinical microbiology diagnostic environment. There are three main applications of …

A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings

HA Thorpe, R Booton, T Kallonen, MJ Gibbon… - Nature …, 2022 - nature.com
The Klebsiella group, found in humans, livestock, plants, soil, water and wild animals, is
genetically and ecologically diverse. Many species are opportunistic pathogens and can …

NDM metallo-β-lactamases and their bacterial producers in health care settings

W Wu, Y Feng, G Tang, F Qiao… - Clinical microbiology …, 2019 - journals.asm.org
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

[KIRJA][B] Antimicrobial resistance and the United Nations sustainable development cooperation framework: Guidance for United Nations Country teams

World Health Organization - 2021 - books.google.com
Given the inter-relatedness of human and animal health, plant production, food safety and
the environment in both the evolution of the AMR problem and solutions to that problem …

Fighting antibiotic resistance in hospital-acquired infections: current state and emerging technologies in disease prevention, diagnostics and therapy

E Avershina, V Shapovalova, G Shipulin - Frontiers in microbiology, 2021 - frontiersin.org
Rising antibiotic resistance is a global threat that is projected to cause more deaths than all
cancers combined by 2050. In this review, we set to summarize the current state of antibiotic …

Application of metagenomic next-generation sequencing in the diagnosis of pulmonary infectious pathogens from bronchoalveolar lavage samples

Y Chen, W Feng, K Ye, L Guo, H **a, Y Guan… - Frontiers in cellular …, 2021 - frontiersin.org
Background Metagenomic next-generation sequencing (mNGS) is a powerful method for
pathogen detection. In this study, we assessed the value of mNGS for bronchoalveolar …

Applications of Raman spectroscopy in bacterial infections: principles, advantages, and shortcomings

L Wang, W Liu, JW Tang, JJ Wang, QH Liu… - Frontiers in …, 2021 - frontiersin.org
Infectious diseases caused by bacterial pathogens are important public issues. In addition,
due to the overuse of antibiotics, many multidrug-resistant bacterial pathogens have been …

[HTML][HTML] Prevotella in Pigs: The Positive and Negative Associations with Production and Health

S Amat, H Lantz, PM Munyaka, BP Willing - Microorganisms, 2020 - mdpi.com
A diverse and dynamic microbial community (known as microbiota) resides within the pig
gastrointestinal tract (GIT). The microbiota contributes to host health and performance by …

Enterococcus spp. as a Producer and Target of Bacteriocins: A Double-Edged Sword in the Antimicrobial Resistance Crisis Context

AC Almeida-Santos, C Novais, L Peixe, AR Freitas - Antibiotics, 2021 - mdpi.com
Enterococcus spp. are one of the most frequent producers of bacteriocins (enterocins),
which provides them with an advantage to compete in their natural environment, which is the …