Locomotion is a universal motor behavior that is expressed as the output of many integrated
brain functions. Locomotion is organized at several levels of the nervous system, with …

Many animals can navigate toward a goal they cannot see based on an internal
representation of that goal in the brain's spatial maps. These maps are organized around …

Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …

In neural networks that store information in their connection weights, there is a tradeoff
between sensitivity and stability,. Connections must be plastic to incorporate new …

Knowing one's own behavioral state has long been theorized as critical for contextualizing
dynamic sensory cues and identifying appropriate future behaviors. Ascending neurons …

Long-lasting internal arousal states motivate and pattern ongoing behaviour, enabling the
temporary emergence of innate behavioural programs that serve the needs of an animal …

Anchoring goals to spatial representations enables flexible navigation but is challenging in
novel environments when both representations must be acquired simultaneously. We …

When an animal moves through the world, its brain receives a stream of information about
the body's translational velocity from motor commands and sensory feedback signals. These …