COVID-19 pandemic has a high mortality rate and is affecting practically the entire world
population. The leading cause of death is severe acute respiratory syndrome as a …

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease characterized by an
abnormal reepithelialisation, an excessive tissue remodelling and a progressive fibrosis …

Background Cytotoxic chemotherapeutics form the cornerstone of systemic treatment of
many cancers. Patients are dosed at maximum tolerated dose (MTD), which is carefully …

Idiopathic pulmonary fibrosis is a terminal lung ailment that shares several pathological and
genetic mechanisms with severe COVID-19. Thymol (THY) is a dietary compound found in …

Fibrosis is a common occurrence following organ injury and failure. To date, there is no
effective treatment for this condition. Melatonin targets numerous molecular pathways, a …

Abstract Melatonin (MT; N‑acetyl‑5‑methoxy‑tryptamine), which has multiple effects and
roles, is secreted from the pineal gland at night according to the daily rhythm. In addition to …

Idiopathic pulmonary fibrosis (IPF) is characterized by the progressive loss of lung function
due to tissue scarring. A variety of pro-inflammatory and pro-fibrogenic factors including …

The chemical composition of Pinus roxburghii bark essential oil (PRO) was qualitatively and
quantitatively determined using GC/FID and GC/MS. The anti-inflammatory activity was …

Idiopathic pulmonary fibrosis (IPF) is a progressive, fibrotic interstitial pneumonia with high
mortality. Melatonin, a hormone predominantly secreted by the pineal gland, has been …

The effect of pachymic acid (PA) on pulmonary fibrosis in rats was expected to be
investigated in this study. Firstly, bleomycin (BLM) was used to establish pulmonary fibrosis …