The roles of extracellular vesicles in the immune system
EI Buzas - Nature Reviews Immunology, 2023 - nature.com
The twenty-first century has witnessed major developments in the field of extracellular
vesicle (EV) research, including significant steps towards defining standard criteria for the …
vesicle (EV) research, including significant steps towards defining standard criteria for the …
Extracellular vesicles as next generation immunotherapeutics
Extracellular vesicles (EVs) function as a mode of intercellular communication and
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
molecular transfer to elicit diverse biological/functional response. Accumulating evidence …
Tumors evade immune cytotoxicity by altering the surface topology of NK cells
X Zheng, Z Hou, Y Qian, Y Zhang, Q Cui, X Wang… - Nature …, 2023 - nature.com
The highly variable response rates to immunotherapies underscore our limited knowledge
about how tumors can manipulate immune cells. Here the membrane topology of natural …
about how tumors can manipulate immune cells. Here the membrane topology of natural …
D Hu, AT Irving - Frontiers in Immunology, 2023 - frontiersin.org
Following viral infection, viral antigens bind specifically to receptors on the surface of
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …
Mechano-modulation of T cells for cancer immunotherapy
Immunotherapy, despite its promise for future anti-cancer approach, faces significant
challenges, such as off-tumor side effects, innate or acquired resistance, and limited …
challenges, such as off-tumor side effects, innate or acquired resistance, and limited …
Coordinating cytoskeleton and molecular traffic in T cell migration, activation, and effector functions
M Mastrogiovanni, M Juzans, A Alcover… - Frontiers in Cell and …, 2020 - frontiersin.org
Dynamic localization of receptors and signaling molecules at the plasma membrane and
within intracellular vesicular compartments is crucial for T lymphocyte sensing …
within intracellular vesicular compartments is crucial for T lymphocyte sensing …