[HTML][HTML] Diabetic macular edema: current understanding, molecular mechanisms and therapeutic implications

J Zhang, J Zhang, C Zhang, J Zhang, L Gu, D Luo… - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), with increasing incidence, is the major cause of vision loss and
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …

Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy

J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy

J Wei, J Mu, Y Tang, D Qin, J Duan, A Wu - Journal of nanobiotechnology, 2023 - Springer
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and
related conditions, pose considerable challenges to effective management and treatment …

Exploring the correlation between the systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), and type 2 diabetic retinopathy

S Wang, X Pan, B Jia, S Chen - Diabetes, Metabolic Syndrome …, 2023 - Taylor & Francis
Purpose Systemic immune inflammation index (SII), systemic inflammatory response index
(SIRI) are new inflammation indicators calculated after integrating multiple indicators in …

Metabolomics of various samples advancing biomarker discovery and pathogenesis elucidation for diabetic retinopathy

X Du, L Yang, L Kong, Y Sun, K Shen, Y Cai… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy (DR) is a universal microvascular complication of diabetes mellitus
(DM), which is the main reason for global sight damage/loss in middle-aged and/or older …

RIP3-mediated microglial necroptosis promotes neuroinflammation and neurodegeneration in the early stages of diabetic retinopathy

Z Huang, J Liang, S Chen, TK Ng, ME Brelén… - Cell Death & …, 2023 - nature.com
Diabetic retinopathy (DR) is a leading cause of blindness that poses significant public health
concerns worldwide. Increasing evidence suggests that neuroinflammation plays a key role …

Vitreous and vision degrading myodesopsia

J Sebag - Progress in Retinal and Eye Research, 2020 - Elsevier
Macromolecules comprise only 2% of vitreous, yet are responsible for its gel state,
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …

Putative biomarkers in tears for diabetic retinopathy diagnosis

M Amorim, B Martins, F Caramelo, C Gonçalves… - Frontiers in …, 2022 - frontiersin.org
Purpose Tear fluid biomarkers may offer a non-invasive strategy for detecting diabetic
patients with increased risk of develo** diabetic retinopathy (DR) or increased disease …

Review of three-dimensional liquid chromatography platforms for bottom-up proteomics

VA Duong, JM Park, H Lee - International Journal of Molecular Sciences, 2020 - mdpi.com
Proteomics is a large-scale study of proteins, aiming at the description and characterization
of all expressed proteins in biological systems. The expressed proteins are typically highly …

[HTML][HTML] Metabolomics in diabetic retinopathy: a systematic review

XW Hou, Y Wang, CW Pan - Investigative Ophthalmology & …, 2021 - tvst.arvojournals.org
Purpose: Diabetic retinopathy (DR), a common microvascular complication of diabetes, is
the leading cause of acquired blindness in the working-age population. Individuals with …