Periods of synchronized myelin changes shape brain function and plasticity

O de Faria Jr, H Pivonkova, B Varga, S Timmler… - Nature …, 2021 - nature.com
Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …

Development of myelinating glia: an overview

CD Cristobal, HK Lee - Glia, 2022 - Wiley Online Library
Myelin is essential to nervous system function, playing roles in saltatory conduction and
trophic support. Oligodendrocytes (OLs) and Schwann cells (SCs) form myelin in the central …

Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension

M Iyer, H Kantarci, MH Cooper, N Ambiel… - Nature …, 2024 - nature.com
Myelin is essential for rapid nerve signaling and is increasingly found to play important roles
in learning and in diverse diseases of the CNS. Morphological parameters of myelin such as …

[HTML][HTML] Life-long oligodendrocyte development and plasticity

A Nishiyama, T Shimizu, A Sherafat… - Seminars in cell & …, 2021 - Elsevier
Oligodendrocyte precursor cells (OPCs) originate in localized germinal zones in the
embryonic neural tube, then migrate and proliferate to populate the entire central nervous …

Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain

CL Cullen, RE Pepper, MT Clutterbuck, KA Pitman… - Cell Reports, 2021 - cell.com
Central nervous system myelination increases action potential conduction velocity.
However, it is unclear how myelination is coordinated to ensure the temporally precise …

Dynamics of mature myelin

LA Osso, EG Hughes - Nature Neuroscience, 2024 - nature.com
Myelin, which is produced by oligodendrocytes, insulates axons to facilitate rapid and
efficient action potential propagation in the central nervous system. Traditionally viewed as a …

Remodelling of myelinated axons and oligodendrocyte differentiation is stimulated by environmental enrichment in the young adult brain

M Nicholson, RJ Wood, DG Gonsalvez… - European Journal of …, 2022 - Wiley Online Library
Oligodendrocyte production and myelination continues lifelong in the central nervous
system (CNS), and all stages of this process can be adaptively regulated by neuronal …

Axoglial interactions in myelin plasticity: evaluating the relationship between neuronal activity and oligodendrocyte dynamics

AY Foster, H Bujalka, B Emery - Glia, 2019 - Wiley Online Library
Myelin is a critical component of the vertebrate nervous system, both increasing the
conduction velocity of myelinated axons and allowing for metabolic coupling between the …

Myelin sheath injury and repairment after subarachnoid hemorrhage

M Chen, P Guo, X Ru, Y Chen, S Zuo… - Frontiers in …, 2023 - frontiersin.org
Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter.
Through classification and analysis of relevant research results, the discussion in this paper …

[HTML][HTML] Building a (w) rapport between neurons and oligodendroglia: reciprocal interactions underlying adaptive myelination

SE Pease-Raissi, JR Chan - Neuron, 2021 - cell.com
Myelin, multilayered lipid-rich membrane extensions formed by oligodendrocytes around
neuronal axons, is essential for fast and efficient action potential propagation in the central …