Non-coding RNAs (ncRNAs) are regulators of intracellular and intercellular signaling in
breast cancer. ncRNAs modulate intracellular signaling to control diverse cellular processes …

Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …

Past studies have shown that amplified insulin-like growth factor 1 (IGF1)/IGF1 receptor
(IGF1-R) signalling has an important role in colorectal cancer (CRC) development …

Mitochondrial function and integrity are vital for the maintenance of cellular homeostasis,
particularly in high-energy demanding cells. Cardiomyocytes have a large number of …

Transcriptomic changes in specific brain regions can influence the risk of alcohol use
disorder (AUD), but the underlying mechanism is not fully understood. We investigated AUD …

Hydrogen sulfide (H 2 S) is an air pollutant, has toxic effects on respiratory tract. However,
the underlying mechanisms of H 2 S induced respiratory toxicity and the roles of long non …

Stroke is one of the leading causes of death and disability worldwide. Because stroke is a
multifactorial disease with a short therapeutic window many clinical stroke trials have failed …

The generation of differentiated and functional neurons is a complex process, which
requires coordinated expression of several proteins and microRNAs (miRNAs). The present …

Cyclin E1, encoded by the CCNE1 gene, promotes G1/S transition, chromosome instability,
and oncogenesis. Here, we show that miR-497 and miR-34a target the 3′-UTR of CCNE1 …

Fetal alcohol spectrum disorders (FASD) are difficult to diagnose since many heavily
exposed infants, at risk for intellectual disability, do not exhibit craniofacial dysmorphology or …