Obesity: epidemiology, pathophysiology, and therapeutics

X Lin, H Li - Frontiers in endocrinology, 2021 - frontiersin.org
Obesity is a complex multifactorial disease that accumulated excess body fat leads to
negative effects on health. Obesity continues to accelerate resulting in an unprecedented …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Short chain fatty acids (SCFAs)-mediated gut epithelial and immune regulation and its relevance for inflammatory bowel diseases

D Parada Venegas, MK De la Fuente… - Frontiers in …, 2019 - frontiersin.org
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel
Diseases (IBD), are caused by a complex interplay between genetic, immunologic, microbial …

Dietary fibre in gastrointestinal health and disease

SK Gill, M Rossi, B Bajka, K Whelan - Nature Reviews Gastroenterology …, 2021 - nature.com
Epidemiological studies have consistently demonstrated the benefits of dietary fibre on
gastrointestinal health through consumption of unrefined whole foods, such as wholegrains …

Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?

S Deleu, K Machiels, J Raes, K Verbeke, S Vermeire - EBioMedicine, 2021 - thelancet.com
The gut microbiome and the intestinal immune system are driving contributors to
inflammatory bowel diseases (IBD). Both have an important signalling factor in common …

Epidemiology and pathogenesis of ulcerative colitis

L Du, C Ha - Gastroenterology Clinics, 2020 - gastro.theclinics.com
Ulcerative colitis (UC) is a chronic immune-mediated inflammatory disorder of the colon
(IBD) that is hypothesized to be related to exposure to environmental risk factors leading to …

Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

The role of short-chain fatty acids in immunity, inflammation and metabolism

Y Yao, X Cai, W Fei, Y Ye, M Zhao… - Critical reviews in food …, 2022 - Taylor & Francis
Short-chain fatty acids (SCFAs) are carboxylic acids with carbon atom numbers less than 6,
which are important metabolites of gut microbiome. Existing research shows that SCFAs …

[HTML][HTML] The gut microbiome, aging, and longevity: a systematic review

VD Badal, ED Vaccariello, ER Murray, KE Yu, R Knight… - Nutrients, 2020 - mdpi.com
Aging is determined by complex interactions among genetic and environmental factors.
Increasing evidence suggests that the gut microbiome lies at the core of many age …

Postbiotics and their potential applications in early life nutrition and beyond

CAM Wegh, SY Geerlings, J Knol, G Roeselers… - International journal of …, 2019 - mdpi.com
Postbiotics are functional bioactive compounds, generated in a matrix during fermentation,
which may be used to promote health. The term postbiotics can be regarded as an umbrella …