A small set of distinctive short RNA molecules are found in the nuclei of all higher eukaryotic
cells and yeast, in protein complexes known as' small nuclear ribonucleoprotein particles', or …

Spliceosomal snRNAs are extensively 2'-O-methylated and pseudouridylated. The modified
nucleotides are relatively highly conserved across species, and are often clustered in …

Background Recently, genomic sequencing efforts were finished for Oryza sativa (cultivated
rice) and Arabidopsis thaliana (Arabidopsis). Additionally, these two plant species have …

The ability of purified Ul small nuclear RNA-protein complexes (Ul snRNPs) to bind in vitro to
two RNAs transcribed from recombinant DNA clones by bacteriophage T7 RNA polymerase …

Two different experimental approaches have provided evidence that both U2 and Ul
snRNPs function in premRNA splicing. When the U2 snRNPs in a nuclear extract are …

Trlmethyl cap** of U2 snRNA has been studied using U2 genes with mutations located in
either the 5'flanking or the coding region. A monomethyl (T-methylguanosine) cap is added …

A database of 209 Drosophila Introns was extracted from Genbank (release number 64.0)
and examined by a number of methods in order to characterize features that might serve as …

All eukaryotic cells contain multiple small nuclear RNAs, designated U-sn At present ten U-
snRNAs have been identified; they account for about 1% total mammalian cellular RNA. Of …

Pseudouridine (Ψ) residues were localized in the Saccharomyces cerevisiae spliceosomal
U small nuclear RNAs (UsnRNAs) by using the chemical map** method. In contrast to …

We have used gene disruption to isolate two talin (−/−) ES cell mutants that contain no intact
talin. The undifferentiated cells (a) were unable to spread on gelatin or laminin and grew as …