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[HTML][HTML] Neuroimmune signaling in alcohol use disorder
EK Erickson, EK Grantham, AS Warden… - Pharmacology …, 2019 - Elsevier
Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for develo** or repurposing effective …
Targeting the neuroimmune system is a new avenue for develo** or repurposing effective …
Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease
K Takahashi, JB Foster, CLG Lin - Cellular and Molecular Life Sciences, 2015 - Springer
Glutamate is the predominant excitatory neurotransmitter in the central nervous system.
Excitatory amino acid transporter 2 (EAAT2) is primarily responsible for clearance of …
Excitatory amino acid transporter 2 (EAAT2) is primarily responsible for clearance of …
Development and evaluation of a calcium alginate based oral ceftriaxone sodium formulation
The purpose of this work was to develop a multiparticulate system exploiting the pH-
sensitive property and biodegradability of calcium alginate beads for intestinal delivery of …
sensitive property and biodegradability of calcium alginate beads for intestinal delivery of …
Glutamatergic transmission in drug reward: implications for drug addiction
MS D'Souza - Frontiers in neuroscience, 2015 - frontiersin.org
Individuals addicted to drugs of abuse such as alcohol, nicotine, cocaine, and heroin are a
significant burden on healthcare systems all over the world. The positive reinforcing …
significant burden on healthcare systems all over the world. The positive reinforcing …
Astroglial correlates of neuropsychiatric disease: From astrocytopathy to astrogliosis
R Kim, KL Healey, MT Sepulveda-Orengo… - Progress in Neuro …, 2018 - Elsevier
Complex roles for astrocytes in health and disease continue to emerge, highlighting this
class of cells as integral to function and dysfunction of the nervous system. In particular …
class of cells as integral to function and dysfunction of the nervous system. In particular …
Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice
A Moshensky, CS Brand, H Alhaddad, J Shin… - Elife, 2022 - elifesciences.org
While health effects of conventional tobacco are well defined, data on va** devices,
including one of the most popular e-cigarettes which have high nicotine levels, are less …
including one of the most popular e-cigarettes which have high nicotine levels, are less …
Neuroimmune mechanisms as novel treatment targets for substance use disorders and associated comorbidities
MD Namba, JM Leyrer-Jackson, EK Nagy… - Frontiers in …, 2021 - frontiersin.org
Recent studies examining the neurobiology of substance abuse have revealed a significant
role of neuroimmune signaling as a mechanism through which drugs of abuse induce …
role of neuroimmune signaling as a mechanism through which drugs of abuse induce …
Targeting glutamate uptake to treat alcohol use disorders
Alcoholism is a serious public health concern that is characterized by the development of
tolerance to alcohol's effects, increased consumption, loss of control over drinking and the …
tolerance to alcohol's effects, increased consumption, loss of control over drinking and the …
Ceftriaxone attenuates ethanol drinking and restores extracellular glutamate concentration through normalization of GLT-1 in nucleus accumbens of male alcohol …
SC Das, BK Yamamoto, AM Hristov, Y Sari - Neuropharmacology, 2015 - Elsevier
Alteration of glutamatergic-neurotransmission is a hallmark of alcohol dependence. We
have previously reported that chronic ethanol-drinking downregulated glutamate transporter …
have previously reported that chronic ethanol-drinking downregulated glutamate transporter …
Immune treatments for alcohol use disorder: A translational framework
LR Meredith, EM Burnette, EN Grodin, MR Irwin… - Brain, behavior, and …, 2021 - Elsevier
While the immune system is essential for survival, an excessive or prolonged inflammatory
response, such as that resulting from sustained heavy alcohol use, can damage the host …
response, such as that resulting from sustained heavy alcohol use, can damage the host …