Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

Inflammation is an immune response that works as a contained fire that is pre-emptively
sparked as a defensive process during infections or upon any kind of tissue insult, and that …

lipoxygenase (12/15-LOX) is an enzyme, which oxidizes polyunsaturated fatty acids,
particularly omega-6 and-3 fatty acids, to generate a number of bioactive lipid metabolites. A …

Omega-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid,
docosapentaenoic acid and docosahexaenoic acid, display a wide range of beneficial …

Specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins are formed by
the consecutive action of 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic …

Obesity is associated with increased risk for infections and poor responses to vaccinations,
which may be due to compromised B cell function. However, there is limited information …

Asthma is a chronic disorder characterized by persistent inflammation of the airways with
mucosal infiltration of eosinophils, T lymphocytes, and mast cells, and release of …

Chronic pain (CP) is a severe clinical entity with devastating physical and emotional
consequences for patients, which can occur in a myriad of diseases. Often, conventional …

An inflammatory response is beneficial to the organism, while an excessive uncontrolled
inflammatory response can lead to the nonspecific killing of tissue cells. Therefore …

Airborne pathogens and environmental stimuli evoke immune responses in the lung. It is
critical to health that these responses be controlled to prevent tissue damage and the …