The skin provides both a physical barrier and an immunologic barrier to external threats. The
protective machinery of the skin has evolved to provide situation-specific responses to …

Psoriasis is a chronic inflammatory skin disease, the immunologic model of which has been
profoundly revised following recent advances in the understanding of its pathophysiology. In …

Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …

The cytokine TSLP has been shown to be a key factor in maintaining immune homeostasis
and regulating inflammatory responses at mucosal barriers. While the role of TSLP in type 2 …

Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine similar to IL-7, whose
gene is located on chromosome 5q22. 1 and it exerts its biological function through the …

Itch (or pruritus) was not previously recognized as a serious symptom of psoriasis. However,
approximately 60–90% of psoriatic patients with pruritus have stated that it deteriorates their …

The pro-inflammatory cytokine thymic stromal lymphopoietin (TSLP) is pivotal to the
pathophysiology of widespread allergic diseases mediated by type 2 helper T cell (Th2) …

Thymic Stromal Lymphopoietin (TSLP) and Interleukin-7 (IL-7) are widely studied cytokines
within distinct branches of immunology. On one hand, TSLP is crucially important for …

T follicular helper cells (Tfh) are important regulators of humoral responses. Human Tfh
polarization pathways have been thus far associated with Th1 and Th17 polarization …

Thymic stromal lymphopoietin (TSLP) was initially demonstrated to be critical in regulating
inflammatory responses among various allergic disorders (such as atopic dermatitis, food …