Pneumococcal capsules and their types: past, present, and future
Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Its
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …
Streptococcus pneumoniae's Virulence and Host Immunity: Aging, Diagnostics, and Prevention
Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …
Development of Next Generation Streptococcus pneumoniae Vaccines Conferring Broad Protection
Streptococcus pneumoniae is a major pathogen causing pneumonia with over 2 million
deaths annually, especially in young children and the elderly. To date, at least 98 different …
deaths annually, especially in young children and the elderly. To date, at least 98 different …
Streptococcus pneumoniae: Invasion and Inflammation
Streptococcus pneumoniae (the pneumoccus) is the leading cause of otitis media,
community-acquired pneumonia, and bacterial meningitis. The success of the …
community-acquired pneumonia, and bacterial meningitis. The success of the …
Sugar-coated killer: serotype 3 pneumococcal disease
Capsular polysaccharide (CPS), which surrounds the bacteria, is one of the most significant
and multifaceted contributors to Streptococcus pneumoniae virulence. Capsule prevents …
and multifaceted contributors to Streptococcus pneumoniae virulence. Capsule prevents …
Nonencapsulated Streptococcus pneumoniae: emergence and pathogenesis
While significant protection from pneumococcal disease has been achieved by the use of
polysaccharide and polysaccharide-protein conjugate vaccines, capsule-independent …
polysaccharide and polysaccharide-protein conjugate vaccines, capsule-independent …
[HTML][HTML] Whole genome sequencing of Streptococcus pneumoniae: development, evaluation and verification of targets for serogroup and serotype prediction using an …
G Kapatai, CL Sheppard, A Al-Shahib, DJ Litt… - PeerJ, 2016 - peerj.com
Streptococcus pneumoniae typically express one of 92 serologically distinct capsule
polysaccharide (cps) types (serotypes). Some of these serotypes are closely related to each …
polysaccharide (cps) types (serotypes). Some of these serotypes are closely related to each …
Host-pathogen interactions in gram-positive bacterial pneumonia
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality
worldwide. Despite broad literature including basic and translational scientific studies, many …
worldwide. Despite broad literature including basic and translational scientific studies, many …
Pneumococcal surface proteins as virulence factors, immunogens, and conserved vaccine targets
Streptococcus pneumoniae is an opportunistic pathogen that causes over 1 million deaths
annually despite the availability of several multivalent pneumococcal conjugate vaccines …
annually despite the availability of several multivalent pneumococcal conjugate vaccines …
[PDF][PDF] Diagnosis of pneumococcal pneumonia: current pitfalls and the way forward
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia.
However, it can also asymptomatically colonize the upper respiratory tract. Because of the …
However, it can also asymptomatically colonize the upper respiratory tract. Because of the …