[HTML][HTML] Toward building mass spectrometry-based metabolomics and lipidomics atlases for biological and clinical research

S Rakusanova, O Fiehn, T Cajka - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Current metabolomics and lipidomics studies are limited in the number of examined
matrices, the breadth and scope of methods, reporting the number of metabolites, and data …

Mass spectrometry imaging: the rise of spatially resolved single-cell omics

H Zhang, DG Delafield, L Li - nature methods, 2023 - nature.com
Increasing evidence suggests that the spatial distribution of biomolecules within cells is a
critical component in deciphering single-cell molecular heterogeneity. State-of-the-art single …

[HTML][HTML] Lipid metabolism around the body clocks

V Petrenko, F Sinturel, H Riezman, C Dibner - Progress in Lipid Research, 2023 - Elsevier
Lipids play important roles in energy metabolism along with diverse aspects of biological
membrane structure, signaling and other functions. Perturbations of lipid metabolism are …

Spatial metabolomics: from a niche field towards a driver of innovation

T Alexandrov - Nature Metabolism, 2023 - nature.com
Spatial metabolomics has matured and is driving innovation in mass spectrometry,
metabolomics and spatial omics. With exciting discoveries, complementary capabilities and …

Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations

AR Lederer, M Leonardi, L Talamanca… - Nature …, 2024 - nature.com
Across biological systems, cells undergo coordinated changes in gene expression, resulting
in transcriptome dynamics that unfold within a low-dimensional manifold. While low …