Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y ** of …
[HTML][HTML] Toward building mass spectrometry-based metabolomics and lipidomics atlases for biological and clinical research
Current metabolomics and lipidomics studies are limited in the number of examined
matrices, the breadth and scope of methods, reporting the number of metabolites, and data …
matrices, the breadth and scope of methods, reporting the number of metabolites, and data …
Mass spectrometry imaging: the rise of spatially resolved single-cell omics
Increasing evidence suggests that the spatial distribution of biomolecules within cells is a
critical component in deciphering single-cell molecular heterogeneity. State-of-the-art single …
critical component in deciphering single-cell molecular heterogeneity. State-of-the-art single …
[HTML][HTML] Lipid metabolism around the body clocks
Lipids play important roles in energy metabolism along with diverse aspects of biological
membrane structure, signaling and other functions. Perturbations of lipid metabolism are …
membrane structure, signaling and other functions. Perturbations of lipid metabolism are …
Spatial metabolomics: from a niche field towards a driver of innovation
T Alexandrov - Nature Metabolism, 2023 - nature.com
Spatial metabolomics has matured and is driving innovation in mass spectrometry,
metabolomics and spatial omics. With exciting discoveries, complementary capabilities and …
metabolomics and spatial omics. With exciting discoveries, complementary capabilities and …
Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations
Across biological systems, cells undergo coordinated changes in gene expression, resulting
in transcriptome dynamics that unfold within a low-dimensional manifold. While low …
in transcriptome dynamics that unfold within a low-dimensional manifold. While low …