Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …

Extracellular vesicles (EVs) have emerged as crucial mediators of intercellular
communication, being involved in a wide array of key biological processes. Eukaryotic cells …

Although gut and lymph node (LN) memory CD4 T cells represent major HIV and simian
immunodeficiency virus (SIV) tissue reservoirs, the study of the role of dendritic cells (DCs) …

Immunomodulatory Siglecs are controlled by their glycoprotein and glycolipid ligands.
Siglec-glycolipid interactions are often studied outside the context of a lipid bilayer, missing …

Human Immunodeficiency Virus (HIV) is still one of the major global health issues, and
despite significant efforts that have been put into studying the pathogenesis of HIV infection …

In metabolic glycoengineering (MGE), cells or animals are treated with unnatural derivatives
of monosaccharides. After entering the cytosol, these sugar analogues are metabolized and …

Extracellular vesicles (EVs) have a significant impact on the pathophysiological processes
associated with various diseases such as tumors, inflammation, and infection. They exhibit …

Glycosphingolipids (GSLs) are a specialized class of membrane lipids composed of a
ceramide backbone and a carbohydrate-rich head group. GSLs populate lipid rafts of the …

Myeloid cells such as monocytes, dendritic cells (DC) and macrophages (MΦ) are key
components of the innate immune system contributing to the maintenance of tissue …

Dendritic cells (DCs) are professional antigen-presenting cells that link innate and adaptive
immunity and are critical for the induction of protective immune responses against …