[HTML][HTML] Circadian disruption and human health

AB Fishbein, KL Knutson, PC Zee - The Journal of clinical investigation, 2021 - jci.org
Circadian disruption is pervasive and can occur at multiple organizational levels,
contributing to poor health outcomes at individual and population levels. Evidence points to …

Circadian rhythms disrupted by light at night and mistimed food intake alter hormonal rhythms and metabolism

OH Meléndez-Fernández, JA Liu… - International journal of …, 2023 - mdpi.com
Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …

[HTML][HTML] Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults

TM Brown, GC Brainard, C Cajochen, CA Czeisler… - PLoS …, 2022 - journals.plos.org
Ocular light exposure has important influences on human health and well-being through
modulation of circadian rhythms and sleep, as well as neuroendocrine and cognitive …

Time-restricted eating to prevent and manage chronic metabolic diseases

A Chaix, ENC Manoogian, GC Melkani… - Annual review of …, 2019 - annualreviews.org
Molecular clocks are present in almost every cell to anticipate daily recurring and
predictable changes, such as rhythmic nutrient availability, and to adapt cellular functions …

Circadian clock genes and the transcriptional architecture of the clock mechanism

KH Cox, JS Takahashi - Journal of molecular endocrinology, 2019 - jme.bioscientifica.com
The mammalian circadian clock has evolved as an adaptation to the 24-h light/darkness
cycle on earth. Maintaining cellular activities in synchrony with the activities of the organism …

[HTML][HTML] Light affects mood and learning through distinct retina-brain pathways

DC Fernandez, PM Fogerson, LL Ospri, MB Thomsen… - Cell, 2018 - cell.com
Light exerts a range of powerful biological effects beyond image vision, including mood and
learning regulation. While the source of photic information affecting mood and cognitive …

The radical-pair mechanism of magnetoreception

PJ Hore, H Mouritsen - Annual review of biophysics, 2016 - annualreviews.org
Although it has been known for almost half a century that migratory birds can detect the
direction of the Earth's magnetic field, the primary sensory mechanism behind this …

The spectral sensitivity of human circadian phase resetting and melatonin suppression to light changes dynamically with light duration

MA St Hilaire, ML Ámundadóttir, SA Rahman… - Proceedings of the …, 2022 - pnas.org
Human circadian, neuroendocrine, and neurobehavioral responses to light are mediated
primarily by melanopsin-containing intrinsically-photosensitive retinal ganglion cells …

Circadian Rhythms and Sleep in Drosophila melanogaster

C Dubowy, A Sehgal - Genetics, 2017 - academic.oup.com
The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

Light as a central modulator of circadian rhythms, sleep and affect

TA LeGates, DC Fernandez, S Hattar - Nature Reviews Neuroscience, 2014 - nature.com
Light has profoundly influenced the evolution of life on earth. As widely appreciated, light
enables us to generate images of our environment. However, light—through intrinsically …