Guidelines and definitions for research on epithelial–mesenchymal transition
Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular
organization from epithelial to mesenchymal phenotypes, which leads to functional changes …
organization from epithelial to mesenchymal phenotypes, which leads to functional changes …
Dynamic EMT: a multi‐tool for tumor progression
S Brabletz, H Schuhwerk, T Brabletz… - The EMBO journal, 2021 - embopress.org
The process of epithelial–mesenchymal transition (EMT) is fundamental for embryonic
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …
Epithelial-mesenchymal plasticity in cancer progression and metastasis
W Lu, Y Kang - Developmental cell, 2019 - cell.com
Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
Regulatory networks defining EMT during cancer initiation and progression
Epithelial to mesenchymal transition (EMT) is essential for driving plasticity during
development, but is an unintentional behaviour of cells during cancer progression. The EMT …
development, but is an unintentional behaviour of cells during cancer progression. The EMT …
Signaling mechanisms of the epithelial-mesenchymal transition
DM Gonzalez, D Medici - Science signaling, 2014 - science.org
The epithelial-mesenchymal transition (EMT) is an essential mechanism in embryonic
development and tissue repair. EMT also contributes to the progression of disease …
development and tissue repair. EMT also contributes to the progression of disease …
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
PA Gregory, AG Bert, EL Paterson, SC Barry… - Nature cell …, 2008 - nature.com
Epithelial to mesenchymal transition (EMT) facilitates tissue remodelling during embryonic
development and is viewed as an essential early step in tumour metastasis. We found that …
development and is viewed as an essential early step in tumour metastasis. We found that …
TGF-β-induced epithelial to mesenchymal transition
J Xu, S Lamouille, R Derynck - Cell research, 2009 - nature.com
During development and in the context of different morphogenetic events, epithelial cells
undergo a process called epithelial to mesenchymal transition or transdifferentiation (EMT) …
undergo a process called epithelial to mesenchymal transition or transdifferentiation (EMT) …
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
J Yang, RA Weinberg - Developmental cell, 2008 - cell.com
The epithelial-mesenchymal transition is a highly conserved cellular program that allows
polarized, immotile epithelial cells to convert to motile mesenchymal cells. This important …
polarized, immotile epithelial cells to convert to motile mesenchymal cells. This important …
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
The molecular mechanisms that underlie tumour progression are still poorly understood, but
recently our knowledge of particular aspects of some of these processes has increased …
recently our knowledge of particular aspects of some of these processes has increased …
Epithelial–mesenchymal plasticity in carcinoma metastasis
JH Tsai, J Yang - Genes & development, 2013 - genesdev.cshlp.org
Tumor metastasis is a multistep process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. Metastasis occurs through a series of steps …
site and form secondary tumors at a distant site. Metastasis occurs through a series of steps …