Sampled-data control of probabilistic boolean control networks: A deep reinforcement learning approach

A Yerudkar, E Chatzaroulas, C Del Vecchio… - Information …, 2023 - Elsevier
The rise of reinforcement learning (RL) has guided a new paradigm: unraveling the
intervention strategies to control systems with unknown dynamics. Model-free RL provides …

Enabling serverless deployment of large-scale ai workloads

A Christidis, S Moschoyiannis, CH Hsu… - IEEE Access, 2020 - ieeexplore.ieee.org
We propose a set of optimization techniques for transforming a generic AI codebase so that
it can be successfully deployed to a restricted serverless environment, without compromising …

Constrained attractor selection using deep reinforcement learning

XS Wang, JD Turner, BP Mann - Journal of Vibration and …, 2021 - journals.sagepub.com
This study describes an approach for attractor selection (or multistability control) in nonlinear
dynamical systems with constrained actuation. Attractor selection is obtained using two …

Deep reinforcement learning for control of probabilistic Boolean networks

G Papagiannis, S Moschoyiannis - … & Their Applications IX: Volume 2 …, 2021 - Springer
Abstract Probabilistic Boolean Networks (PBNs) were introduced as a computational model
for the study of complex dynamical systems, such as Gene Regulatory Networks (GRNs) …

Deep reinforcement learning for stabilization of large-scale probabilistic Boolean networks

S Moschoyiannis, E Chatzaroulas… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
The ability to direct a probabilistic Boolean network (PBN) to the desired state is important to
applications such as targeted therapeutics in cancer biology. Reinforcement learning (RL) …

State-flipped control and Q-learning for finite horizon output tracking of Boolean control networks

C Sun, H Li - International Journal of Systems Science, 2023 - Taylor & Francis
This article explores the state-flipped control mechanism for the finite horizon output tracking
of Boolean control networks (BCNs) subject to a time-varying reference output trajectory …

Output Tracking of Switched Boolean Networks via Self-Triggered Control

Q Zhang, J Feng, F **ao, B Wei - IEEE Transactions on Control …, 2024 - ieeexplore.ieee.org
This paper investigates the output tracking problem of switched Boolean networks using self-
triggered control. Firstly, by virtue of the constructed auxiliary system, two necessary and …

A structural characterisation of the mitogen-activated protein kinase network in cancer

E Chatzaroulas, V Sliogeris, P Victori, FM Buffa… - Symmetry, 2022 - mdpi.com
Gene regulatory networks represent collections of regulators that interact with each other
and with other molecules to govern gene expression. Biological signalling networks model …

Inferring probabilistic boolean networks from steady-state gene data samples

V Šliogeris, L Maglaras, S Moschoyiannis - International Conference on …, 2022 - Springer
Abstract Probabilistic Boolean Networks have been proposed for estimating the behaviour of
dynamical systems as they combine rule-based modelling with uncertainty principles …