Heterosis and hybrid crop breeding: a multidisciplinary review

MR Labroo, AJ Studer, JE Rutkoski - Frontiers in Genetics, 2021 - frontiersin.org
Although hybrid crop varieties are among the most popular agricultural innovations, the
rationale for hybrid crop breeding is sometimes misunderstood. Hybrid breeding is slower …

Adaptive introgression in animals: examples and comparison to new mutation and standing variation as sources of adaptive variation

PW Hedrick - Molecular ecology, 2013 - Wiley Online Library
Adaptive genetic variation has been thought to originate primarily from either new mutation
or standing variation. Another potential source of adaptive variation is adaptive variants from …

Genetic rescue: A critique of the evidence supports maximizing genetic diversity rather than minimizing the introduction of putatively harmful genetic variation

K Ralls, P Sunnucks, RC Lacy, R Frankham - Biological Conservation, 2020 - Elsevier
Genetic rescue–ameliorating inbreeding depression and restoring genetic diversity of inbred
populations through gene flow-is valuable in wildlife conservation. Empirically validated …

Y recombination arrest and degeneration in the absence of sexual dimorphism

T Lenormand, D Roze - Science, 2022 - science.org
Current theory proposes that degenerated sex chromosomes—such as the mammalian Y—
evolve through three steps:(i) recombination arrest, linking male-beneficial alleles to the Y …

Estimating the mutation load in human genomes

BM Henn, LR Botigué, CD Bustamante… - Nature Reviews …, 2015 - nature.com
Next-generation sequencing technology has facilitated the discovery of millions of genetic
variants in human genomes. A sizeable fraction of these variants are predicted to be …

Distance from sub-Saharan Africa predicts mutational load in diverse human genomes

BM Henn, LR Botigué, S Peischl… - Proceedings of the …, 2016 - National Acad Sciences
The Out-of-Africa (OOA) dispersal∼ 50,000 y ago is characterized by a series of founder
events as modern humans expanded into multiple continents. Population genetics theory …

The interplay of demography and selection during maize domestication and expansion

L Wang, TM Beissinger, A Lorant, C Ross-Ibarra… - Genome biology, 2017 - Springer
Background The history of maize has been characterized by major demographic events,
including population size changes associated with domestication and range expansion, and …

The utility of Fisher's geometric model in evolutionary genetics

O Tenaillon - Annual review of ecology, evolution, and …, 2014 - annualreviews.org
The accumulation of data on the genomic bases of adaptation has triggered renewed
interest in theoretical models of adaptation. Among these models, Fisher's geometric model …

Incomplete dominance of deleterious alleles contributes substantially to trait variation and heterosis in maize

J Yang, S Mezmouk, A Baumgarten, ES Buckler… - PLoS …, 2017 - journals.plos.org
Deleterious alleles have long been proposed to play an important role in patterning
phenotypic variation and are central to commonly held ideas explaining the hybrid vigor …

Mutation load: the fitness of individuals in populations where deleterious alleles are abundant

AF Agrawal, MC Whitlock - Annual Review of Ecology, Evolution …, 2012 - annualreviews.org
Many multicellular eukaryotes have reasonably high per-generation mutation rates.
Consequently, most populations harbor an abundance of segregating deleterious alleles …