Abstract Objective: Intraindividual variability (IIV), generally defined as short-term variations
in behavior, has been proposed as a sign of subtle early impairment in neurodegenerative …

Myelin water fraction (MWF) imaging has emerged as a promising magnetic resonance
imaging (MRI) biomarker for investigating brain function and composition. This …

Background Disruption of sleep and circadian rhythmicity is a core feature of mood disorders
and might be associated with increased susceptibility to such disorders. Previous studies in …

Schizophrenia and bipolar disorder (BD) may be disorders of accelerated aging. Direct
comparison of healthy aging populations with schizophrenia and BD patients across the …

Although cross-sectional studies suggest that cognitive aging starts in midlife, few
longitudinal studies have documented within-individual declines in cognitive performance …

Attention deficits have been proven in patients with major depressive disorder (MDD).
However, a detailed characterization of attention deficits in MDD was unclear. The aim of …

The aging brain undergoes major changes in its topology. The mechanisms by which the
brain mitigates age-associated changes in topology to maintain robust control of brain …

Objectives: 1. Assess validity of the Oxford Cognitive Screen (OCS-Plus), a domain-specific
cognitive assessment designed for low-literacy settings, especially in low-and middle …

Therapies targeted at fundamental processes of aging may hold great promise for
enhancing the health of a wide population by delaying or preventing a range of age-related …

The patient who sustains a traumatic brain injury (TBI) typically undergoes neuroimaging
studies, usually in the form of computed tomography (CT) and magnetic resonance imaging …