Ultrasound as a versatile tool for short-and long-term improvement and monitoring of brain function

DG Blackmore, D Razansky, J Götz - Neuron, 2023 - cell.com
Treating the brain with focused ultrasound (FUS) at low intensities elicits diverse responses
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …

An Activatable NIR‐II Fluorescent Reporter for In Vivo Imaging of Amyloid‐β Plaques

J Miao, M Miao, Y Jiang, M Zhao, Q Li… - Angewandte Chemie …, 2023 - Wiley Online Library
Fluorescence imaging in the second near‐infrared (NIR‐II) window holds great promise for
in vivo visualization of amyloid‐β (Aβ) pathology, which can facilitate characterization and …

Deep tissue photoacoustic imaging with light and sound

L Menozzi, J Yao - npj Imaging, 2024 - nature.com
Photoacoustic computed tomography (PACT) can harvest diffusive photons to image the
optical absorption contrast of molecules in a scattering medium, with ultrasonically-defined …

Single-domain antibody–based noninvasive in vivo imaging of α-synuclein or tau pathology

Y Jiang, Y Lin, S Krishnaswamy, R Pan, Q Wu… - Science …, 2023 - science.org
Intracellular deposition of α-synuclein and tau are hallmarks of synucleinopathies and
tauopathies, respectively. Recently, several dye-based imaging probes with selectivity for …

A Highly Bright Near‐Infrared Afterglow Luminophore for Activatable Ultrasensitive In Vivo Imaging

L Yang, M Zhao, W Chen, J Zhu, W Xu, Q Li… - Angewandte …, 2024 - Wiley Online Library
Afterglow luminescence imaging probes, with long‐lived emission after cessation of light
excitation, have drawn increasing attention in biomedical imaging field owing to their …

[HTML][HTML] Aquaporin 4 is differentially increased and dislocated in association with tau and amyloid-beta

V Kecheliev, L Boss, U Maheshwari, U Konietzko… - Life sciences, 2023 - Elsevier
Aims Neurovascular-glymphatic dysfunction plays an important role in Alzheimer's disease
and has been analysed mainly in relation to amyloid-beta (Aβ) pathology. Here, we aim to …

Masked cross-domain self-supervised deep learning framework for photoacoustic computed tomography reconstruction

H Lan, L Huang, X Wei, Z Li, J Lv, C Ma, L Nie, J Luo - Neural Networks, 2024 - Elsevier
Accurate image reconstruction is crucial for photoacoustic (PA) computed tomography
(PACT). Recently, deep learning has been used to reconstruct PA images with a supervised …

In vivo three-dimensional brain imaging with chemiluminescence probes in Alzheimer's disease models

J Zhang, C Wickizer, W Ding, R Van… - Proceedings of the …, 2023 - National Acad Sciences
Optical three-dimensional (3D) molecular imaging is highly desirable for providing precise
distribution of the target-of-interest in disease models. However, such 3D imaging is still far …

Atomic‐Thin 2D Copper Sulfide Nanocrystals with over 94% Photothermal Conversion Efficiency as Superior NIR‐II Photoacoustic Agents

M Su, Z Wu, T Yan, N Li, X Li, T Hou… - Advanced Functional …, 2024 - Wiley Online Library
Exploring photothermal nanomaterials is essential for new energy and biomedical
applications; however, preparing materials with intense absorption, highly efficient light‐to …

[HTML][HTML] Learning spatially variant degradation for unsupervised blind photoacoustic tomography image restoration

K Tang, S Zhang, Y Wang, X Zhang, Z Liu, Z Liang… - Photoacoustics, 2023 - Elsevier
Photoacoustic tomography (PAT) images contain inherent distortions due to the imaging
system and heterogeneous tissue properties. Improving image quality requires the removal …