Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms
L Xu, Y Li, Y Dai, J Peng - Pharmacological research, 2018 - Elsevier
Epidemiological studies have implied that diabetes mellitus (DM) will become an epidemic
accompany with metabolic and endocrine disorders worldwide. Most of DM patients are …
accompany with metabolic and endocrine disorders worldwide. Most of DM patients are …
Preclinical evidence for the pharmacological actions of naringin: a review
S Bharti, N Rani, B Krishnamurthy, DS Arya - Planta medica, 2014 - thieme-connect.com
Naringin, chemically 4′, 5, 7-trihydroxyflavanone-7-rhamnoglucoside, is a major flavanone
glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. It has been …
glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. It has been …
Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies
Objective To determine whether individual fruits are differentially associated with risk of type
2 diabetes. Design Prospective longitudinal cohort study. Setting Health professionals in the …
2 diabetes. Design Prospective longitudinal cohort study. Setting Health professionals in the …
Naringin improves diet-induced cardiovascular dysfunction and obesity in high carbohydrate, high fat diet-fed rats
Obesity, insulin resistance, hypertension and fatty liver, together termed metabolic
syndrome, are key risk factors for cardiovascular disease. Chronic feeding of a diet high in …
syndrome, are key risk factors for cardiovascular disease. Chronic feeding of a diet high in …
Dipeptidyl peptidase (DPP)-IV inhibitors with antioxidant potential isolated from natural sources: A novel approach for the management of diabetes
Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia that is predominantly
caused by insulin resistance or impaired insulin secretion, along with disturbances in …
caused by insulin resistance or impaired insulin secretion, along with disturbances in …
Berry and citrus phenolic compounds inhibit dipeptidyl peptidase IV: Implications in diabetes management
Beneficial health effects of fruits and vegetables in the diet have been attributed to their high
flavonoid content. Dipeptidyl peptidase IV (DPP‐IV) is a serine aminopeptidase that is a …
flavonoid content. Dipeptidyl peptidase IV (DPP‐IV) is a serine aminopeptidase that is a …
Food-derived dipeptidyl-peptidase IV inhibitors as a potential approach for glycemic regulation–Current knowledge and future research considerations
IME Lacroix, ECY Li-Chan - Trends in Food Science & Technology, 2016 - Elsevier
Background Diabetes, which currently affects 1 in 11 adults, is considered one of the biggest
worldwide health crises of the 21st century. Over the last decade, synthetic inhibitors of the …
worldwide health crises of the 21st century. Over the last decade, synthetic inhibitors of the …
Review of factors affecting citrus polyphenol bioavailability and their importance in designing in vitro, animal, and intervention studies
Evidence from in vitro, animal, and human studies links citrus fruit consumption with several
health‐promoting effects. However, many in vitro studies disregard bioavailability data, a key …
health‐promoting effects. However, many in vitro studies disregard bioavailability data, a key …
Anthocyanins and proanthocyanidins from blueberry–blackberry fermented beverages inhibit markers of inflammation in macrophages and carbohydrate‐utilizing …
Scope Berries are an excellent source of dietary flavonoids which have several health
benefits. Methods and results We evaluated well‐characterized anthocyanins (ANCs) and …
benefits. Methods and results We evaluated well‐characterized anthocyanins (ANCs) and …
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus
N Li, LJ Wang, B Jiang, X Li, C Guo, S Guo… - European Journal of …, 2018 - Elsevier
Diabetes is a fast growing chronic metabolic disorder around the world. Dipeptidyl peptidase-
4 (DPP-4) is a new promising target during type 2 diabetes glycemic control. Thus, a number …
4 (DPP-4) is a new promising target during type 2 diabetes glycemic control. Thus, a number …