Quantitative phase imaging based on holography: trends and new perspectives
Abstract In 1948, Dennis Gabor proposed the concept of holography, providing a pioneering
solution to a quantitative description of the optical wavefront. After 75 years of development …
solution to a quantitative description of the optical wavefront. After 75 years of development …
Label-free biomedical optical imaging
Label-free optical imaging employs natural and non-destructive approaches to visualize
biomedical samples for both biological assays and clinical diagnosis. At present, this field …
biomedical samples for both biological assays and clinical diagnosis. At present, this field …
Stain-free identification of cell nuclei using tomographic phase microscopy in flow cytometry
Quantitative phase imaging has gained popularity in bioimaging because it can avoid the
need for cell staining, which, in some cases, is difficult or impossible. However, as a result …
need for cell staining, which, in some cases, is difficult or impossible. However, as a result …
Holotomography
Holotomography (HT) represents a 3D, label-free optical imaging methodology that
leverages refractive index as an inherent quantitative contrast for imaging. This technique …
leverages refractive index as an inherent quantitative contrast for imaging. This technique …
Machine learning for sperm selection
Infertility rates and the number of couples seeking fertility care have increased worldwide
over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are …
over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are …
High spatial and temporal resolution synthetic aperture phase microscopy
A new optical microscopy technique, termed high spatial and temporal resolution synthetic
aperture phase microscopy (HISTR-SAPM), is proposed to improve the lateral resolution of …
aperture phase microscopy (HISTR-SAPM), is proposed to improve the lateral resolution of …
Simulating nature in sperm selection for assisted reproduction
ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …
Multiscale label-free volumetric holographic histopathology of thick-tissue slides with subcellular resolution
Histopathology relies upon the staining and sectioning of biological tissues, which can be
laborious and may cause artifacts and distort tissues. We develop label-free volumetric …
laborious and may cause artifacts and distort tissues. We develop label-free volumetric …
Dehydration of plant cells shoves nuclei rotation allowing for 3D phase-contrast tomography
Single-cell phase-contrast tomography promises to become decisive for studying 3D
intracellular structures in biology. It involves probing cells with light at wide angles, which …
intracellular structures in biology. It involves probing cells with light at wide angles, which …
Full-field optical coherence microscopy enables high-resolution label-free imaging of the dynamics of live mouse oocytes and early embryos
High quality label-free imaging of oocytes and early embryos is essential for accurate
assessment of their developmental potential, a key element of assisted reproduction …
assessment of their developmental potential, a key element of assisted reproduction …