The concept and development of bone/cartilage organoids are rapidly gaining momentum,
providing opportunities for both fundamental and translational research in bone biology …

3D printed/bioprinted tissue constructs are utilized for the regeneration of damaged tissues
and as in vitro models. Most of the fabricated 3D constructs fail to undergo functional …

Since three-dimensional (3D) bioprinting has emerged, it has continuously to evolved as a
revolutionary technology in surgery, offering new paradigms for reconstructive and …

A porous structure is essential for bone implants because it increases the bone ingrowth
space and improves mechanical and biological properties. The biomimetically designed …

Bone can adapt its microstructure to mechanical loads through mechanoregulation of the
(re) modeling process. This process has been investigated in vivo using time-lapsed micro …

With the increasing importance of preclinical evaluation of newly developed drugs or
treatments, in vitro organ or disease models are necessary. Although various organ-specific …

Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells in
vitro by engineering approaches, has aroused increasing interest given that it maintains the …

Organoids have emerged as a powerful platform for studying complex biological processes
and diseases in vitro. However, most studies have focused on individual organoids …

3D bioprinting has shown great promise in tissue engineering and regenerative medicine for
creating patient-specific tissue scaffolds and medicinal devices. The quickness, accurate …

Human in vitro bone remodeling models, using osteoclast–osteoblast cocultures, can
facilitate the investigation of human bone remodeling while reducing the need for animal …