Evaluating machine learning methodologies for identification of cancer driver genes
SJ Malebary, YD Khan - Scientific reports, 2021 - nature.com
Cancer is driven by distinctive sorts of changes and basic variations in genes. Recognizing
cancer driver genes is basic for accurate oncological analysis. Numerous methodologies to …
cancer driver genes is basic for accurate oncological analysis. Numerous methodologies to …
SPalmitoylC-PseAAC: A sequence-based model developed via Chou's 5-steps rule and general PseAAC for identifying S-palmitoylation sites in proteins
S-Palmitoylation is a uniquely reversible and biologically important post-translational
modification as it plays an essential role in a variety of cellular processes including signal …
modification as it plays an essential role in a variety of cellular processes including signal …
SPrenylC-PseAAC: A sequence-based model developed via Chou's 5-steps rule and general PseAAC for identifying S-prenylation sites in proteins
The protein prenylation (or S-prenylation) is one of the most essential modifications,
required for the association of membrane of a plethora of signalling proteins with the key …
required for the association of membrane of a plethora of signalling proteins with the key …
Identification of 4-carboxyglutamate residue sites based on position based statistical feature and multiple classification
AA Shah, YD Khan - Scientific Reports, 2020 - nature.com
Glutamic acid is an alpha-amino acid used by all living beings in protein biosynthesis. One
of the important glutamic acid modifications is post-translationally modified 4 …
of the important glutamic acid modifications is post-translationally modified 4 …
iPhosH-PseAAC: Identify phosphohistidine sites in proteins by blending statistical moments and position relative features according to the Chou's 5-step rule and …
Protein phosphorylation is one of the key mechanism in prokaryotes and eukaryotes and is
responsible for various biological functions such as protein degradation, intracellular …
responsible for various biological functions such as protein degradation, intracellular …
iSUMOK-PseAAC: prediction of lysine sumoylation sites using statistical moments and Chou's PseAAC
Sumoylation is the post-translational modification that is involved in the adaption of the cells
and the functional properties of a large number of proteins. Sumoylation has key importance …
and the functional properties of a large number of proteins. Sumoylation has key importance …
iTSP-PseAAC: identifying tumor suppressor proteins by using fully connected neural network and PseAAC
Background: The uncontrolled growth due to accumulation of genetic and epigenetic
changes as a result of loss or reduction in the normal function of Tumor Suppressor Genes …
changes as a result of loss or reduction in the normal function of Tumor Suppressor Genes …
pSSbond-PseAAC: Prediction of disulfide bonding sites by integration of PseAAC and statistical moments
The structure of protein gains additional stability against various detrimental effects by the
presence of disulfide bonds. The formation of correct disulfide bonds between cysteine …
presence of disulfide bonds. The formation of correct disulfide bonds between cysteine …
ProtoPred: advancing oncological research through identification of proto-oncogene proteins
Proto-oncogenes are the genes that have the potential to transform normal cells into cancer
cells as a result of mutations. They usually contain encoding of proteins whose function is to …
cells as a result of mutations. They usually contain encoding of proteins whose function is to …
Prediction of N-linked glycosylation sites using position relative features and statistical moments
Glycosylation is one of the most complex post translation modification in eukaryotic cells.
Almost 50% of the human proteome is glycosylated as glycosylation plays a vital role in …
Almost 50% of the human proteome is glycosylated as glycosylation plays a vital role in …