Mutational landscape of BRCA gene mutations in Indian breast cancer patients: retrospective insights from a diagnostic lab

R Chikkala, D Bhayal, N Rani, R Modali… - Egyptian Journal of …, 2024 - Springer
Abstract Background Presence of Germline mutations in the BRCA 1 and BRCA 2 genes is
the most significant epidemiological factor for breast cancer (BC), where germline BRCA1 (g …

Mendelian randomization analyses support causal relationships between HPV infection and colorectal cancer

B Pei, P Liu, S Peng, F Zhou - Discover Oncology, 2024 - Springer
Abstract Background Human Papillomavirus (HPV) infections leading to a variety of
diseases are a global public health issue. Despite the well-established link between HPV …

[HTML][HTML] Advancements in Ovarian Cancer Research: Targeting DNA Repair Mechanisms and the Role of DNA Polymerase β Inhibitors

A Patra, A Samanta, A Chakraborty… - Biosciences …, 2024 - biotech-asia.org
Background: Exposure to mutagens causes DNA damage, which, if not repaired properly,
can lead to diseases like cancer. Ovarian cancer is a major concern for women globally …