Fuchs endothelial corneal dystrophy: The vicious cycle of Fuchs pathogenesis
Fuchs endothelial corneal dystrophy (FECD) is the most common primary corneal
endothelial dystrophy and the leading indication for corneal transplantation worldwide …
endothelial dystrophy and the leading indication for corneal transplantation worldwide …
Fuchs endothelial corneal dystrophy: clinical, genetic, pathophysiologic, and therapeutic aspects
M Matthaei, A Hribek, T Clahsen… - Annual review of …, 2019 - annualreviews.org
Fuchs endothelial corneal dystrophy (FECD) is a bilateral corneal endothelial disorder and
the most common cause of corneal transplantation worldwide. Professor Ernst Fuchs …
the most common cause of corneal transplantation worldwide. Professor Ernst Fuchs …
RNA phase transitions in repeat expansion disorders
A Jain, RD Vale - Nature, 2017 - nature.com
Expansions of short nucleotide repeats produce several neurological and neuromuscular
disorders including Huntington disease, muscular dystrophy, and amyotrophic lateral …
disorders including Huntington disease, muscular dystrophy, and amyotrophic lateral …
[HTML][HTML] Elimination of toxic microsatellite repeat expansion RNA by RNA-targeting Cas9
Microsatellite repeat expansions in DNA produce pathogenic RNA species that cause
dominantly inherited diseases such as myotonic dystrophy type 1 and 2 (DM1/2) …
dominantly inherited diseases such as myotonic dystrophy type 1 and 2 (DM1/2) …
E proteins and ID proteins: helix-loop-helix partners in development and disease
LH Wang, NE Baker - Developmental cell, 2015 - cell.com
The basic Helix-Loop-Helix (bHLH) proteins represent a well-known class of transcriptional
regulators. Many bHLH proteins act as heterodimers with members of a class of ubiquitous …
regulators. Many bHLH proteins act as heterodimers with members of a class of ubiquitous …
[HTML][HTML] TCF4-mediated Fuchs endothelial corneal dystrophy: Insights into a common trinucleotide repeat-associated disease
MP Fautsch, ED Wieben, KH Baratz… - Progress in retinal and …, 2021 - Elsevier
Fuchs endothelial corneal dystrophy (FECD) is a common cause for heritable visual loss in
the elderly. Since the first description of an association between FECD and common …
the elderly. Since the first description of an association between FECD and common …
Transcription factor 4 and its association with psychiatric disorders
The human transcription factor 4 gene (TCF4) encodes a helix–loop–helix transcription
factor widely expressed throughout the body and during neural development. Mutations in …
factor widely expressed throughout the body and during neural development. Mutations in …
Fuchs endothelial corneal dystrophy: current perspectives
G Vedana, G Villarreal Jr, AS Jun - Clinical ophthalmology, 2016 - Taylor & Francis
Fuchs endothelial corneal dystrophy (FECD) is the most common corneal dystrophy and
frequently results in vision loss. Hallmarks of the disease include loss of corneal endothelial …
frequently results in vision loss. Hallmarks of the disease include loss of corneal endothelial …
[HTML][HTML] Current understanding of the pathogenesis of Fuchs' endothelial corneal dystrophy
GG Nanda, DP Alone - Molecular vision, 2019 - ncbi.nlm.nih.gov
Fuchs' endothelial corneal dystrophy (FECD) is the most prominent reason for corneal-
endothelial transplantations across the globe. The disease pathophysiology manifests …
endothelial transplantations across the globe. The disease pathophysiology manifests …
Intron retention induced by microsatellite expansions as a disease biomarker
Expansions of simple sequence repeats, or microsatellites, have been linked to∼ 30
neurological–neuromuscular diseases. While these expansions occur in coding and …
neurological–neuromuscular diseases. While these expansions occur in coding and …