Experimental evolution for cell biology
Evolutionary cell biology explores the origins, principles, and core functions of cellular
features and regulatory networks through the lens of evolution. This emerging field relies …
features and regulatory networks through the lens of evolution. This emerging field relies …
Use of zebrafish embryos to reproduce human norovirus and to evaluate human norovirus infectivity decay after UV treatment
This study reports an essential improvement of the method for replication of human
norovirus (HNoV) with the use of zebrafish (Danio rerio) embryos. With three HNoV …
norovirus (HNoV) with the use of zebrafish (Danio rerio) embryos. With three HNoV …
Improving the Detection and Understanding of Infectious Human Norovirus in Food and Water Matrices: A Review of Methods and Emerging Models
Human norovirus (HuNoV) is a leading global cause of viral gastroenteritis, contributing to
numerous outbreaks and illnesses annually. However, conventional cell culture systems …
numerous outbreaks and illnesses annually. However, conventional cell culture systems …
Adaptive truncation of the S gene in IBV during chicken embryo passaging plays a crucial role in its attenuation
R Liang, K Liu, Y Li, X Zhang, L Duan, M Huang… - PLoS …, 2024 - journals.plos.org
Like all coronaviruses, infectious bronchitis virus, the causative agent of infectious bronchitis
in chickens, exhibits a high mutation rate. Adaptive mutations that arise during the …
in chickens, exhibits a high mutation rate. Adaptive mutations that arise during the …
Recapitulation of the Powassan virus life cycle in cell culture
J Song, J Hong, C Yang, Y Zhang, Z Li, P He, Q Ding - Mbio, 2024 - Am Soc Microbiol
Powassan virus (POWV) is a tick-borne flavivirus known for causing fatal neuroinvasive
diseases in humans. Recently, there has been a noticeable increase in POWV infections …
diseases in humans. Recently, there has been a noticeable increase in POWV infections …
[HTML][HTML] Experimental evolution of an RNA virus in Caenorhabditis elegans
The discovery of Orsay virus (OrV), the first virus infecting wild populations of Caenorhabditis
elegans, has boosted studies of viral immunity pathways in this nematode. Considering the …
elegans, has boosted studies of viral immunity pathways in this nematode. Considering the …
Murine norovirus mutants adapted to replicate in human cells reveal a post-entry restriction
MR Budicini, VJ Rodriguez-Irizarry, RW Maples… - Journal of …, 2024 - Am Soc Microbiol
ABSTRACT RNA viruses lack proofreading in their RNA polymerases and therefore exist as
genetically diverse populations. By exposing these diverse viral populations to selective …
genetically diverse populations. By exposing these diverse viral populations to selective …
Application route and immune status of the host determine safety and oncolytic activity of oncolytic coxsackievirus B3 variant PD-H
A Hazini, B Dieringer, K Klingel, M Pryshliak, A Geisler… - Viruses, 2021 - mdpi.com
The coxsackievirus B3 strain PD-0 has been proposed as a new oncolytic virus for the
treatment of colorectal carcinoma. Here, we generated a cDNA clone of PD-0 and analyzed …
treatment of colorectal carcinoma. Here, we generated a cDNA clone of PD-0 and analyzed …
The mutational landscape of SARS-CoV-2 provides new insight into viral evolution and fitness
Although vaccines and treatments have strengthened our ability to combat the COVID-19
pandemic, new variants of the SARS-CoV-2 continue to emerge in human populations …
pandemic, new variants of the SARS-CoV-2 continue to emerge in human populations …
Factors That Influence Murine Norovirus Stability and Tropism
MR Budicini - 2024 - utswmed-ir.tdl.org
In this work I investigated factors that influence murine norovirus stability and tropism
through two independent projects. Murine norovirus (MNV) is a model system used to study …
through two independent projects. Murine norovirus (MNV) is a model system used to study …