c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges
c-Jun N-terminal kinases (JNKs), first characterized as stress-activated members of the
mitogen-activated protein kinase (MAPK) family, have become a focus of inhibitor screening …
mitogen-activated protein kinase (MAPK) family, have become a focus of inhibitor screening …
Expression of Concern: The pathophysiological and immunological background of the monkeypox virus infection: An update
In addition to the COVID‐19 waves, the globe is facing global monkeypox (MPX) outbreak.
MPX is an uncommon zoonotic infection characterized by symptoms similar to smallpox. It is …
MPX is an uncommon zoonotic infection characterized by symptoms similar to smallpox. It is …
The poxvirus vectors MVA and NYVAC as gene delivery systems for vaccination against infectious diseases and cancer
CE Gómez, JL Nájera, M Krupa… - Current gene …, 2008 - ingentaconnect.com
Recombinants based on poxviruses have been used extensively as gene delivery systems
to study many biological functions of foreign genes and as vaccines against many …
to study many biological functions of foreign genes and as vaccines against many …
MVA and NYVAC as vaccines against emergent infectious diseases and cancer
CE Gomez, JL Najera, M Krupa… - Current gene …, 2011 - ingentaconnect.com
Recombinants based on poxviruses have been used extensively as gene delivery systems
to study many biological functions of foreign genes and as vaccines against many …
to study many biological functions of foreign genes and as vaccines against many …
[HTML][HTML] Evolution of the orthopoxvirus core genome
Orthopoxviruses comprise several relevant pathogens, including the causative agent of
smallpox and monkeypox virus. Analysis of orthopoxvirus genome evolution mainly focused …
smallpox and monkeypox virus. Analysis of orthopoxvirus genome evolution mainly focused …
[HTML][HTML] Genomic and transcriptomic analysis of the recent Mpox outbreak
Abstract The Mpox (formerly named Monkeypox) virus is the etiological cause of a recent
multi-country outbreak, with thousands of distinct cases detected outside the endemic areas …
multi-country outbreak, with thousands of distinct cases detected outside the endemic areas …
Orthopoxvirus targets for the development of new antiviral agents
MN Prichard, ER Kern - Antiviral research, 2012 - Elsevier
Investments in the development of new drugs for orthopoxvirus infections have fostered new
avenues of research, provided an improved understanding of orthopoxvirus biology and …
avenues of research, provided an improved understanding of orthopoxvirus biology and …
[HTML][HTML] Attenuation of monkeypox virus by deletion of genomic regions
JG Lopera, EA Falendysz, TE Rocke, JE Osorio - Virology, 2015 - Elsevier
Monkeypox virus (MPXV) is an emerging pathogen from Africa that causes disease similar to
smallpox. Two clades with different geographic distributions and virulence have been …
smallpox. Two clades with different geographic distributions and virulence have been …
Viral manipulation of cell death
ZF Zakeri, JE McLean, A Ruck… - Current …, 2008 - ingentaconnect.com
Elucidation of the mechanisms behind cell death has brought with it an appreciation for viral
strategies that target these pathways as a means to promote viral propagation while …
strategies that target these pathways as a means to promote viral propagation while …
Interference with p53 functions in human viral infections, a target for novel antiviral strategies?
PA Lazo, CR Santos - Reviews in medical virology, 2011 - Wiley Online Library
Viral infections cause a major stress in host cells. The cellular responses to stress are
mediated by p53, which by deregulation of cell cycle and apoptosis, may also be part of the …
mediated by p53, which by deregulation of cell cycle and apoptosis, may also be part of the …