A major aim in structural cell biology is to analyze intact cells in three dimensions, visualize
subcellular structures, and even localize proteins at the best possible resolution in three …

Light microscopes are the cell and developmental biologists'“best friend,” providing a means
to see structures and follow dynamics from the protein to the organism level. A huge …

During cell division, chromosome congression to the spindle center, their orientation along
the spindle long axis and alignment at the metaphase plate depend on interactions between …

Microtubule-severing proteins (MTSPs) play important roles in mitosis and interphase.
However, to the best of our knowledge, no previous studies have evaluated the role of …

Background As an extension of electron tomography (ET), serial section electron
tomography (serial section ET) aims to align the tomographic images of multiple thick tissue …

In many animal species, the oocyte meiotic spindle, which is required for chromosome
segregation, forms without centrosomes. In some systems, Ran-GEF on chromatin initiates …

During mitosis microtubules self-organize to form a bipolar mitotic spindle structure, which
positions the sister chromatids on the spindle mid-plane and separates them afterwards …

Oocyte meiotic spindles mediate the expulsion of ¾ of the genome into polar bodies to
generate diploid zygotes in nearly all animal species. Failures in this process result in …

We present a software‐assisted workflow for the alignment and matching of filamentous
structures across a three‐dimensional (3D) stack of serial images. This is achieved by …

Cytoskeletal networks are the main actuators of cellular mechanics, and a foundational
example for active matter physics. In cytoskeletal networks, motion is generated on small …