Mechanisms of lineage specification in Caenorhabditis elegans

J Liu, JI Murray - Genetics, 2023 - academic.oup.com
The studies of cell fate and lineage specification are fundamental to our understanding of
the development of multicellular organisms. Caenorhabditis elegans has been one of the …

Evolutionary Change in Gut Specification in Caenorhabditis Centers on the GATA Factor ELT-3 in an Example of Developmental System Drift

G Broitman-Maduro, MF Maduro - Journal of Developmental Biology, 2023 - mdpi.com
Cells in a develo** animal embryo become specified by the activation of cell-type-specific
gene regulatory networks. The network that specifies the gut in the nematode …

The GATA factor ELT-3 specifies endoderm in Caenorhabditis angaria in an ancestral gene network

G Broitman-Maduro, S Sun, T Kikuchi… - …, 2022 - journals.biologists.com
Endoderm specification in Caenorhabditis elegans occurs through a network in which
maternally provided SKN-1/Nrf, with additional input from POP-1/TCF, activates the GATA …

The Molecular Basis of Differentiation Wave Activity in Embryogenesis

B Alicea, S Bastani, NK Gordon, S Crawford-Young… - BioSystems, 2024 - Elsevier
As development varies greatly across the tree of life, it may seem difficult to suggest a model
that proposes a single mechanism for understanding collective cell behaviors and the …

Transcriptome profiling of the Caenorhabditis elegans intestine reveals that ELT-2 negatively and positively regulates intestinal gene expression within the context of …

RTP Williams, DC King, IR Mastroianni, JL Hill… - Genetics, 2023 - academic.oup.com
ELT-2 is the major transcription factor (TF) required for Caenorhabditis elegans intestinal
development. ELT-2 expression initiates in embryos to promote development and then …

[HTML][HTML] Philosophically Specified Types of Methods Important for Theoretical Natural Science

J Kubrycht - Open Journal of Philosophy, 2024 - scirp.org
In accordance with current philosophical opinions, four classical and one more recently
proposed types of methods frequently used in theoretical natural science are specified here …

Investigation of transcriptional dynamics in the Caenorhabditis elegans intestine gene regulatory network

RTP Williams - 2022 - search.proquest.com
ELT-2 is the major transcription factor required for the activation of Caenorhabditis elegans
intestinal development. ELT-2 expression initiates in embryos to promote development and …