Non-coding RNAs as mediators of epigenetic changes in malignancies
S Kumar, EA Gonzalez, P Rameshwar, JP Etchegaray - Cancers, 2020 - mdpi.com
Simple Summary This review discusses the role of non-coding RNAs (ncRNAs) in cancer
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …
MicroRNA-125 in immunity and cancer
JK Wang, Z Wang, G Li - Cancer letters, 2019 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that play a wide variety of critical roles in
different biological processes by post-transcriptionally regulating gene expression. They …
different biological processes by post-transcriptionally regulating gene expression. They …
New developments on the Encyclopedia of DNA Elements (ENCODE) data portal
Abstract The Encyclopedia of DNA Elements (ENCODE) is an ongoing collaborative
research project aimed at identifying all the functional elements in the human and mouse …
research project aimed at identifying all the functional elements in the human and mouse …
The emerging roles of miR-125b in cancers
Y Wang, G Zeng, Y Jiang - Cancer management and research, 2020 - Taylor & Francis
MicroRNAs (miRNAs) are endogenous, noncoding, single-stranded RNA molecules of 22
nucleotides in length. MiRNAs have both tumor-suppressive properties and oncogenic …
nucleotides in length. MiRNAs have both tumor-suppressive properties and oncogenic …
Essential functions of miR‐125b in cancer
MicroRNAs (miRNAs) are small and highly conserved non‐coding RNAs that silence target
mRNAs, and compelling evidence suggests that they play an essential role in the …
mRNAs, and compelling evidence suggests that they play an essential role in the …
MicroRNAs: Tiny regulators of gene expression with pivotal roles in normal B-Cell development and B-Cell chronic lymphocytic leukemia
Simple Summary The involvement of miRNAs in physiological cellular processes has been
well documented. The development of B cells, which is dictated by a miRNA-transcription …
well documented. The development of B cells, which is dictated by a miRNA-transcription …
Get me out of here: Sphingosine 1‐phosphate signaling and T cell exit from tissues during an immune response
VM Hallisey, SR Schwab - Immunological Reviews, 2023 - Wiley Online Library
During an immune response, the duration of T cell residence in lymphoid and non‐lymphoid
tissues likely affects T cell activation, differentiation, and memory development. The factors …
tissues likely affects T cell activation, differentiation, and memory development. The factors …
MiR-21–3p triggers cardiac fibroblasts pyroptosis in diabetic cardiac fibrosis via inhibiting androgen receptor
P Shi, XD Zhao, KH Shi, XS Ding, H Tao - Experimental Cell Research, 2021 - Elsevier
Aims/hypothesis MicroRNA-21 has been implicated in diabetic complication, including
diabetic cardiomyopathy. However, there is limited information regarding the biological role …
diabetic cardiomyopathy. However, there is limited information regarding the biological role …
miRNA-mediated control of B cell responses in immunity and SLE
Loss of B cell tolerance is central to autoimmune diseases such as systemic lupus
erythematosus (SLE). As such, the mechanisms involved in B cell development, maturation …
erythematosus (SLE). As such, the mechanisms involved in B cell development, maturation …
The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice
Communication between osteoblasts and osteoclasts plays a key role in bone metabolism.
We describe here an unexpected role for matrix vesicles (MVs), which bud from bone …
We describe here an unexpected role for matrix vesicles (MVs), which bud from bone …