Bromelain a potential bioactive compound: a comprehensive overview from a pharmacological perspective

AJ Chakraborty, S Mitra, TE Tallei, AM Tareq, F Nainu… - Life, 2021 - mdpi.com
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple
stems. It contains several thiol endopeptidases and is extracted and purified via several …

[HTML][HTML] Natural bioactive molecules: an alternative approach to the treatment and control of COVID-19

F Islam, S Bibi, AFK Meem, MM Islam… - International Journal of …, 2021 - mdpi.com
Several coronaviruses (CoVs) have been associated with serious health hazards in recent
decades, resulting in the deaths of thousands around the globe. The recent coronavirus …

Potential of Plant Bioactive Compounds as SARS‐CoV‐2 Main Protease (Mpro) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study

TE Tallei, SG Tumilaar, NJ Niode, fnm Fatimawali… - …, 2020 - Wiley Online Library
Since the outbreak of the COVID‐19 (coronavirus disease 19) pandemic, researchers have
been trying to investigate several active compounds found in plants that have the potential to …

Efficacy of Phytochemicals Derived from Avicennia officinalis for the Management of COVID-19: A Combined In Silico and Biochemical Study

S Mahmud, GK Paul, M Afroze, S Islam, SBR Gupt… - Molecules, 2021 - mdpi.com
The recent coronavirus disease 2019 (COVID-19) pandemic is a global threat for healthcare
management and the economic system, and effective treatments against the pathogenic …

[HTML][HTML] Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through …

M Rudrapal, I Celik, J Khan, MA Ansari… - Journal of King Saud …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus
disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The global …

[HTML][HTML] In silico evaluation of Iranian medicinal plant phytoconstituents as inhibitors against main protease and the receptor-binding domain of SARS-CoV-2

SS Mousavi, A Karami, TM Haghighi, SG Tumilaar… - Molecules, 2021 - mdpi.com
The novel coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), which initially appeared in Wuhan, China, in …

[HTML][HTML] A comprehensive update on the bioactive compounds from seagrasses

CMP Gono, P Ahmadi, T Hertiani, E Septiana, MY Putra… - Marine Drugs, 2022 - mdpi.com
Marine angiosperms produce a wide variety of secondary metabolites with unique structural
features that have the potential to be developed as effective and potent drugs for various …

In silico Study of Antiviral Activity of Polyphenol Compounds from Ocimum basilicum by Molecular Docking, ADMET, and Drug-Likeness Analysis

D Kurnia, SA Putri, SG Tumilaar… - … and Applications in …, 2023 - Taylor & Francis
Aim The SARS-CoV-2 virus is a disease that has mild to severe effects on patients, which
can even lead to death. One of the enzymes that act as DNA replication is the main …

[HTML][HTML] Phytochemicals from Leucas zeylanica Targeting Main Protease of SARS-CoV-2: Chemical Profiles, Molecular Docking, and Molecular Dynamics …

M Dutta, AM Tareq, A Rakib, S Mahmud, SA Sami… - Biology, 2021 - mdpi.com
Simple Summary Molecular docking in conjunction with molecular dynamics simulation was
accomplished as they extend an ample opportunity to screen plausible inhibitors of the main …

Phenolic Compounds from Ocimum basilicum Revealed as Antibacterial by Experimental and Computational Screening‐Based Studies against Oral Infections

SA Putri, E Julaeha, N Kagawa… - Journal of Chemistry, 2024 - Wiley Online Library
Dental infections are initiated by Streptococcus sanguinis and Streptococcus mutans
through the biofilm formation. In streptococcal, the ComA enzyme catalyzes the first step to …