Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Today's biologics manufacturing practices incur high costs to the drug makers, which can
contribute to high prices for patients. Timely investment in the development and …

The changing landscape of the biopharmaceutical market is driving a paradigm shift toward
continuous manufacturing. To date, integrated continuous bioprocessing has not been …

Biopharmaceuticals have emerged as powerful therapeutic agents, revolutionizing the
treatment landscape for various diseases, including cancer, infectious diseases …

Continuous integrated bioprocessing has elicited considerable interest from the biopharma
industry for the many purported benefits it promises. Today many major biopharma …

Continuous production delivers higher productivity and better quality than traditional batch-
wise approaches. It intensifies production lowering capital cost and enables better control …

Control of column loading in Protein A chromatography is a crucial part of development of
robust and flexible process platforms for continuous production of monoclonal antibody …

Narrow residence time distributions (RTDs) are desirable in many chemical engineering
processes. However, when a system operates in the laminar flow regime, significant fluid …

Continuous precipitation is a new unit operation for the continuous capture of antibodies.
The capture step is based on continuous precipitation with PEG6000 and Zn++ in a tubular …

Advances in precipitation have demonstrated the capability of purifying therapeutic proteins
such as antibodies from biological sources in a scalable and cost-effective manner. We …