Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents

XR Xu, GM Yousef, H Ni - Blood, The Journal of the American …, 2018 - ashpublications.org
Platelets have long been recognized as key players in hemostasis and thrombosis;
however, growing evidence suggests that they are also significantly involved in cancer, the …

Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond

XR Xu, D Zhang, BE Oswald, N Carrim… - Critical reviews in …, 2016 - Taylor & Francis
Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …

Pathophysiology of immune thrombocytopenia

J Li, JA Sullivan, H Ni - Current opinion in hematology, 2018 - journals.lww.com
Recent evidence of distinct ITP pathophysiology has opened new exploratory avenues for
disease management. We will discuss the utility of investigations into these mechanisms of …

Platelets, protean cells with all-around functions and multifaceted pharmacological applications

C Puricelli, E Boggio, CL Gigliotti, I Stoppa… - International Journal of …, 2023 - mdpi.com
Platelets, traditionally known for their roles in hemostasis and coagulation, are the most
prevalent blood component after erythrocytes (150,000–400,000 platelets/μL in healthy …

[HTML][HTML] GPIbα is the driving force of hepatic thrombopoietin generation

D Karakas, M Xu, H Ni - Research and Practice in Thrombosis and …, 2021 - Elsevier
Thrombopoietin (TPO), a glycoprotein hormone produced predominantly in the liver, plays
important roles in the hematopoietic stem cell (HSC) niche, and is essential for …

Platelet Desialylation: Novel Mechanisms of Immune Suppression

J Li - 2022 - search.proquest.com
Platelets are small, versatile blood cells critical to thrombosis and hemostasis. Platelets are
also increasingly recognized for their essential roles in modulating the immune response …