[HTML][HTML] Bone tissue engineering in the treatment of bone defects

N Xue, X Ding, R Huang, R Jiang, H Huang, X Pan… - Pharmaceuticals, 2022 - mdpi.com
Bones play an important role in maintaining exercise and protecting organs. Bone defect, as
a common orthopedic disease in clinics, can cause tremendous damage with long treatment …

Recent advances in 3D printing of smart scaffolds for bone tissue engineering and regeneration

X Yuan, W Zhu, Z Yang, N He, F Chen… - Advanced …, 2024 - Wiley Online Library
The repair and functional reconstruction of bone defects resulting from severe trauma,
surgical resection, degenerative disease, and congenital malformation pose significant …

Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

H Wei, J Cui, K Lin, J **e, X Wang - Bone research, 2022 - nature.com
Bone defects combined with tumors, infections, or other bone diseases are challenging in
clinical practice. Autologous and allogeneic grafts are two main traditional remedies, but …

3D/4D printed bio-piezoelectric smart scaffolds for next-generation bone tissue engineering

A Chen, J Su, Y Li, H Zhang, Y Shi… - International Journal of …, 2023 - iopscience.iop.org
Piezoelectricity in native bones has been well recognized as the key factor in bone
regeneration. Thus, bio-piezoelectric materials have gained substantial attention in repairing …

Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promotes anti-inflammatory polarization of macrophages and bone repair via MAPK/JNK …

H Wu, H Dong, Z Tang, Y Chen, Y Liu, M Wang, X Wei… - Biomaterials, 2023 - Elsevier
Bone regeneration is a highly synchronized process that requires multiple biochemical,
bioelectrical, mechanical, and other physiological cues. The restoration and delivery of …

Natural piezoelectric biomaterials: a biocompatible and sustainable building block for biomedical devices

R Wang, J Sui, X Wang - ACS nano, 2022 - ACS Publications
The piezoelectric effect has been widely observed in biological systems, and its applications
in biomedical field are emerging. Recent advances of wearable and implantable biomedical …

Self-promoted electroactive biomimetic mineralized scaffolds for bacteria-infected bone regeneration

Z Li, D He, B Guo, Z Wang, H Yu, Y Wang, S **… - Nature …, 2023 - nature.com
Infected bone defects are a major challenge in orthopedic treatment. Native bone tissue
possesses an endogenous electroactive interface that induces stem cell differentiation and …

Bone repair biomaterials: a perspective from immunomodulation

Y Wang, H Zhang, Y Hu, Y **g… - Advanced Functional …, 2022 - Wiley Online Library
With an increasingly aging society, bone defects and fractures have become significant
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …

Neuro–bone tissue engineering: emerging mechanisms, potential strategies, and current challenges

W Sun, B Ye, S Chen, L Zeng, H Lu, Y Wan, Q Gao… - Bone research, 2023 - nature.com
The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

Construction of bio‐piezoelectric platforms: From structures and synthesis to applications

Q Xu, X Gao, S Zhao, YN Liu, D Zhang… - Advanced …, 2021 - Wiley Online Library
Piezoelectric materials, with their unique ability for mechanical‐electrical energy conversion,
have been widely applied in important fields such as sensing, energy harvesting …