Sarcopenia: aging-related loss of muscle mass and function
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …
diminishes quality of life, and can lead to fall-related injuries, which require costly …
Physiology of astroglia
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …
immunology and flow cytometry community. They provide the theory and key practical …
[HTML][HTML] Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis
In the adult hippocampus, neuroprogenitor cells in the subgranular zone (SGZ) of the
dentate gyrus give rise to newborn neuroblasts. However, only a small subset of these cells …
dentate gyrus give rise to newborn neuroblasts. However, only a small subset of these cells …
The cell biology of neurogenesis
M Götz, WB Huttner - Nature reviews Molecular cell biology, 2005 - nature.com
During the development of the mammalian central nervous system, neural stem cells and
their derivative progenitor cells generate neurons by asymmetric and symmetric divisions …
their derivative progenitor cells generate neurons by asymmetric and symmetric divisions …
Characteristics of blood–brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells
The blood–brain barrier (BBB) protects the brain and maintains neuronal homeostasis. BBB
properties can vary between brain regions to support regional functions, yet how BBB …
properties can vary between brain regions to support regional functions, yet how BBB …
Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging
In the adult brain, the neural stem cell (NSC) pool comprises quiescent and activated
populations with distinct roles. Transcriptomic analysis revealed that quiescent and activated …
populations with distinct roles. Transcriptomic analysis revealed that quiescent and activated …
Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing
The dentate gyrus of the hippocampus is a brain region in which neurogenesis persists into
adulthood; however, the relationship between developmental and adult dentate gyrus …
adulthood; however, the relationship between developmental and adult dentate gyrus …
Bioinspired neuron-like electronics
As an important application of functional biomaterials, neural probes have contributed
substantially to studying the brain. Bioinspired and biomimetic strategies have begun to be …
substantially to studying the brain. Bioinspired and biomimetic strategies have begun to be …
Prospective identification and purification of quiescent adult neural stem cells from their in vivo niche
P Codega, V Silva-Vargas, A Paul… - Neuron, 2014 - cell.com
Adult neurogenic niches harbor quiescent neural stem cells; however, their in vivo identity
has been elusive. Here, we prospectively isolate GFAP+ CD133+(quiescent neural stem …
has been elusive. Here, we prospectively isolate GFAP+ CD133+(quiescent neural stem …