Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

A review of colorectal cancer in terms of epidemiology, risk factors, development, symptoms and diagnosis

T Sawicki, M Ruszkowska, A Danielewicz… - Cancers, 2021 - mdpi.com
Simple Summary According to the available data, colorectal cancer (CRC) is one of the most
common malignant neoplasms. Depending on the location, type of cancer or gender, it is …

Gut microbiota, inflammatory bowel disease and colorectal cancer

AEV Quaglio, TG Grillo… - World journal of …, 2022 - pmc.ncbi.nlm.nih.gov
The gut microbiota is a complex community of microorganisms that inhabit the digestive
tracts of humans, living in symbiosis with the host. Dysbiosis, characterized by an imbalance …

Colorectal cancer: from risk factors to oncogenesis

VA Ionescu, G Gheorghe, N Bacalbasa, AL Chiotoroiu… - Medicina, 2023 - mdpi.com
Colorectal cancer is the second leading cause of cancer-related mortality worldwide.
Numerous pathophysiological mechanisms, such as abnormal cell proliferation, cell …

'Green'nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases

M Zu, D **e, BSB Canup, N Chen, Y Wang, R Sun… - Biomaterials, 2021 - Elsevier
Although synthesized nanotherapeutics (NTs) are attractive for the oral treatment of colon
diseases, their clinical translations are constrained by the unsatisfactory therapeutic …

Intestinal epithelial glycosylation in homeostasis and gut microbiota interactions in IBD

MR Kudelka, SR Stowell, RD Cummings… - Nature reviews …, 2020 - nature.com
Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

[HTML][HTML] Beneficial properties of bromelain

P Hikisz, J Bernasinska-Slomczewska - Nutrients, 2021 - mdpi.com
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

Prognostic value of pan-immune-inflammation value in colorectal cancer patients: a systematic review and meta-analysis

XC Yang, H Liu, DC Liu, C Tong, XW Liang… - Frontiers in …, 2022 - frontiersin.org
Background The pan-immune-inflammation value (PIV) has been reported as a novel
prognostic biomarker in multiple malignancies. The aim of this study is to investigate the …

Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022 - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

New insights into natural products that target the gut microbiota: Effects on the prevention and treatment of colorectal cancer

L Lu, J Dong, Y Liu, Y Qian, G Zhang, W Zhou… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignant carcinomas. CRC is
characterized by asymptomatic onset, and most patients are already in the middle and …