Advances in multiplexed techniques for the detection and quantification of microRNAs

T Jet, G Gines, Y Rondelez, V Taly - Chemical Society Reviews, 2021 - pubs.rsc.org
MicroRNA detection is currently a crucial analytical chemistry challenge: almost 2000
papers were referenced in PubMed in 2018 and 2019 for the keywords “miRNA detection …

The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review

BF Far, K Vakili, M Fathi, S Yaghoobpoor, M Bhia… - Life sciences, 2023 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

dbDEMC 3.0: functional exploration of differentially expressed miRNAs in cancers of human and model organisms

F Xu, Y Wang, Y Ling, C Zhou, H Wang… - Genomics …, 2022 - academic.oup.com
M icroRNAs (miRNAs) are important regulators in gene expression. The dysregulation of
miRNA expression is widely reported in the transformation from physiological to pathological …

lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling

Y Lu, X Zhao, Q Liu, C Li, R Graves-Deal, Z Cao… - Nature medicine, 2017 - nature.com
De novo and acquired resistance, which are largely attributed to genetic alterations, are
barriers to effective anti-epidermal-growth-factor-receptor (EGFR) therapy. To generate …

Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway

F Li, L Zhang, W Li, J Deng, J Zheng, M An, J Lu… - …, 2015 - pmc.ncbi.nlm.nih.gov
Circular RNAs with exonic sequences represent a special form of non-coding RNAs,
discovered by analyzing a handful of transcribed genes. It has been observed that circular …

[HTML][HTML] Genetics and molecular pathogenesis of gastric adenocarcinoma

P Tan, KG Yeoh - Gastroenterology, 2015 - Elsevier
Gastric cancer (GC) is globally the fifth most common cancer and third leading cause of
cancer death. A complex disease arising from the interaction of environmental and host …

LncRNA GClnc1 promotes gastric carcinogenesis and may act as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern

TT Sun, J He, Q Liang, LL Ren, TT Yan, TC Yu… - Cancer …, 2016 - aacrjournals.org
Long noncoding RNAs (lncRNA) play a role in carcinogenesis. However, the function of
lncRNAs in human gastric cancer remains largely unknown. In this study, we identified a …

Prognostic role of circulating exosomal miRNAs in multiple myeloma

S Manier, CJ Liu, H Avet-Loiseau, J Park… - Blood, The Journal …, 2017 - ashpublications.org
Exosomes, secreted by several cell types, including cancer cells, can be isolated from the
peripheral blood and have been shown to be powerful markers of disease progression in …

Genetics of gastric cancer

MH McLean, EM El-Omar - Nature reviews Gastroenterology & …, 2014 - nature.com
Gastric cancer remains highly prevalent and accounts for a notable proportion of global
cancer mortality. This cancer is also associated with poor survival rates. Understanding the …