Immune recognition occurs at specialized cell‐cell junctions when immune cells and target
cells physically touch. In this junction, groups of receptor‐ligand complexes assemble and …

Cells are the basic structural and functional units of organisms. Dynamic analysis and
manipulation of specific components in living cells would provide valuable information for …

Molecular forces generated by cell receptors are infrequent and transient, and hence difficult
to detect. Here we report an assay that leverages the CRISPR-associated protein 12a …

Adoptive T lymphocyte (T cell) transfer and tumour‐specific peptide vaccines are innovative
cancer therapies. An accurate assessment of the specific reactivity of T cell receptors (TCRs) …

Mechanical forces drive critical cellular processes that are reflected in mechanical
phenotypes, or mechanotypes, of cells and their microenvironment. We present here …

Mechanotransduction, the process by which cells respond to tension transmitted through
various supramolecular linkages, is important for understanding cellular behavior. Tension …

Tension gauge tethers (TGTs), short DNA segments serving as extracellular tension
sensors, are instrumental in assessing the tension dynamics in mechanotransduction. These …

Mechanical forces are crucial for biological processes such as T cell antigen recognition. A
suite of molecular tension probes to measure pulling forces have been reported over the …

Investigation of the biological system reveals many underlying principles that govern the
regular life processes. Recently, the analysis of tiny mechanical forces associated with many …

Biological systems perceive and respond to mechanical forces, generating mechanical cues
to regulate life processes. Analyzing biomechanical forces has profound significance for …