The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Peptide design and self-assembly into targeted nanostructure and functional materials

NJ Sinha, MG Langenstein, DJ Pochan… - Chemical …, 2021 - ACS Publications
Peptides have been extensively utilized to construct nanomaterials that display targeted
structure through hierarchical assembly. The self-assembly of both rationally designed …

Prospects and challenges of dynamic DNA nanostructures in biomedical applications

T Tian, Y Li, Y Lin - Bone Research, 2022 - nature.com
The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

Aptamer–protein interactions: from regulation to biomolecular detection

C Ji, J Wei, L Zhang, X Hou, J Tan, Q Yuan… - Chemical …, 2023 - ACS Publications
Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Functional DNA-based cytoskeletons for synthetic cells

P Zhan, K Jahnke, N Liu, K Göpfrich - Nature chemistry, 2022 - nature.com
The cytoskeleton is an essential component of a cell. It controls the cell shape, establishes
the internal organization, and performs vital biological functions. Building synthetic …

[HTML][HTML] Pursuing excitonic energy transfer with programmable DNA-based optical breadboards

D Mathur, SA Díaz, N Hildebrandt… - Chemical Society …, 2023 - pubs.rsc.org
DNA nanotechnology has now enabled the self-assembly of almost any prescribed 3-
dimensional nanoscale structure in large numbers and with high fidelity. These structures …

DNA origami: scaffolds for creating higher order structures

F Hong, F Zhang, Y Liu, H Yan - Chemical reviews, 2017 - ACS Publications
DNA has become one of the most extensively used molecular building blocks for
engineering self-assembling materials. DNA origami is a technique that uses hundreds of …

Protein assembly: versatile approaches to construct highly ordered nanostructures

Q Luo, C Hou, Y Bai, R Wang, J Liu - Chemical Reviews, 2016 - ACS Publications
Nature endows life with a wide variety of sophisticated, synergistic, and highly functional
protein assemblies. Following Nature's inspiration to assemble protein building blocks into …

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

PS Kwon, S Ren, SJ Kwon, ME Kizer, L Kuo, M **e… - Nature …, 2020 - nature.com
DNA, when folded into nanostructures with a specific shape, is capable of spacing and
arranging binding sites into a complex geometric pattern with nanometre precision. Here we …

Three-dimensional structures self-assembled from DNA bricks

Y Ke, LL Ong, WM Shih, P Yin - science, 2012 - science.org
We describe a simple and robust method to construct complex three-dimensional (3D)
structures by using short synthetic DNA strands that we call “DNA bricks.” In one-step …